Chemotherapy Agents

DRUG6 trials

Sponsors

National Taiwan University Hospital, Takeda, Kochi University

Conditions

LeukemiaPancreatic Cancer MetastaticPediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL)Ph+ Mixed Phenotype Acute Leukemia (MPAL)Philadelphia Chromosome-Like ALL (Ph-like ALL)Refractory Lupus NephritisRefractory Systemic SclerosisRelapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

Phase 1

A Study of Ponatinib With Chemotherapy in Children, Teenagers, and Adults With Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia

TerminatedNCT04501614

TakedaPediatric Philadelphia Chromosome-positive Acute Lymphoblastic Leukemia (Ph+ALL), Philadelphia Chromosome-Like ALL (Ph-like ALL), Ph+ Mixed Phenotype Acute Leukemia (MPAL)

Start: 2021-02-24End: 2024-07-19Updated: 2025-10-02

A Study of GDX012 in Adults With Relapsed or Refractory Acute Myeloid Leukemia

TerminatedNCT05886491

Start: 2023-07-11End: 2025-11-30Updated: 2026-04-01

A Study of TAK-007 in Adults With Refractory Lupus Nephritis (LN) or Refractory Systemic Sclerosis (SSc)

WithdrawnNCT06377228

TakedaRefractory Lupus Nephritis, Refractory Systemic Sclerosis

Start: 2025-06-13End: 2030-09-02Updated: 2025-04-06

Phase 2

A Study of TAK-007 in Adults With Relapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

Active, not recruitingNCT05020015

TakedaRelapsed or Refractory (r/r) B-cell Non-Hodgkin Lymphoma (NHL)

Start: 2021-11-12End: 2038-12-20Updated: 2026-03-31

Unknown Phase

Detection of Human Chorionic Gonadotropin by Interferometry in Gestational Trophoblastic Disease

National Taiwan University HospitalTrophoblastic Neoplasms

Start: 2005-09-30End: 2014-12-31Target: 30Updated: 2014-12-08

Does Recurrent Pancreatic Cancer Really Have Similar Outcome Compared With Primary Metastatic Pancreatic Cancer?

CompletedNCT06921252

Kochi UniversityPancreatic Cancer Metastatic

Start: 2010-01-01End: 2025-03-01Updated: 2025-04-10

Related Papers

Does Recurrent Pancreatic Cancer Have Similar Outcomes Compared With Primary Metastatic Pancreatic Cancer?

2026-03-01

Efficacy and Safety of TAK-007, Cord Blood-Derived CD19 CAR-NK Cells, in Adult Patients with Relapsed/Refractory (R/R) B-Cell Non-Hodgkin Lymphoma (NHL)

Blood2024-11-053 citations

Population Pharmacokinetics of Ponatinib in Healthy Adult Volunteers and Patients With Hematologic Malignancies and Model‐Informed Dose Selection for Pediatric Development

The Journal of Clinical Pharmacology2021-10-2620 citations

A Phase 1/2 Study to Evaluate the Safety and Efficacy of Ponatinib with Chemotherapy in Pediatric Patients with Philadelphia Chromosome-Positive (Ph+) Acute Lymphoblastic Leukemia (ALL)

Blood2020-11-041 citations