Cesium-131

DEVICE2 trials

Sponsors

Sidney Kimmel Cancer Center at Thomas Jefferson University, University of Cincinnati

Conditions

HNSCCRecurrent Head and Neck Carcinoma

Early Phase 1

Surgical Resection and Intraoperative Cesium-131 Brachytherapy for Head and Neck Cancer

CompletedNCT02467738

Sidney Kimmel Cancer Center at Thomas Jefferson UniversityRecurrent Head and Neck Carcinoma

Start: 2015-03-17End: 2020-05-28Updated: 2025-09-19

Phase 1

Trial Combining Pembrolizumab and Cesium 131 Brachytherapy With Salvage Surgery in HNSCC

Active, not recruitingNCT04340258

University of CincinnatiHNSCC

Start: 2021-02-04End: 2026-09-04Target: 50Updated: 2026-06-09

Related Papers

Neoadjuvant/adjuvant pembrolizumab and surgery + cesium-131 in recurrent HNSCC: A multicenter phase I/IIb trial.

Journal of Clinical Oncology2025-05-28

Multi-Institutional Study Validates Safety of Intraoperative Cesium-131 Brachytherapy for Treatment of Recurrent Head and Neck Cancer

Frontiers in Oncology2021-11-268 citations

Permanent Interstitial Cesium-131 Brachytherapy in Treating High-Risk Recurrent Head and Neck Cancer: A Prospective Pilot Study

Frontiers in Oncology2021-03-185 citations