Celgosivir

DRUG6 trials

Sponsors

BioWest Therapeutics Inc, Singapore General Hospital

Conditions

Chronic Hepatitis CDengue FeverHepatitis C, Chronic

Phase 1

Celgosivir as a Treatment Against Dengue

CompletedNCT01619969

Singapore General HospitalDengue Fever

Start: 2012-07-31End: 2013-07-31Updated: 2013-12-02

Celgosivir or Modipafant as Treatment for Adult Participants With Uncomplicated Dengue Fever in Singapore

WithdrawnNCT02569827

Singapore General HospitalDengue Fever

Start: 2018-12-31End: 2019-08-08Updated: 2020-03-23

Phase 2

A Study to Evaluate the Safety and Efficacy of Celgosivir in Patients With Chronic Hepatitis C Genotype 1 Infection

CompletedNCT00157534

BioWest Therapeutics IncHepatitis C, Chronic

Start: 2004-10-31End: 2005-08-31Target: 43Updated: 2005-09-12

A Study to Evaluate the Safety and Efficacy of Celgosivir and Peginterferon Alfa-2b, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype 1 Infection

CompletedNCT00217139

BioWest Therapeutics IncHepatitis C, Chronic

Start: 2005-09-30End: 2006-09-30Target: 60Updated: 2006-09-29

An Extension Study to Evaluate the Safety and Efficacy of Celgosivir and Peginterferon Alfa-2b, With or Without Ribavirin, in Patients With Chronic Hepatitis C Genotype 1 Infection

CompletedNCT00292084

BioWest Therapeutics IncHepatitis C, Chronic

Start: 2006-02-28End: 2007-10-31Target: 60Updated: 2008-01-21

A Study to Evaluate the Safety, Antiviral Effect, and Pharmacokinetics of Celgosivir in Combination With Peginterferon Alfa-2b and Ribavirin in Treatment-Naïve Patients With Chronic Hepatitis C

BioWest Therapeutics IncChronic Hepatitis C

Start: 2006-06-30End: 2008-12-31Target: 50Updated: 2008-04-08

Related Papers

Extended Evaluation of Virological, Immunological and Pharmacokinetic Endpoints of CELADEN: A Randomized, Placebo-Controlled Trial of Celgosivir in Dengue Fever Patients

PLoS neglected tropical diseases2016-08-1068 citations

Optimizing celgosivir therapy in mouse models of dengue virus infection of serotypes 1 and 2: The search for a window for potential therapeutic efficacy.

2016-01-1360 citations

Efficacy and safety of celgosivir in patients with dengue fever (CELADEN): a phase 1b, randomised, double-blind, placebo-controlled, proof-of-concept trial.

2014-05-28178 citations