CEA-targeted CAR-T cells

BIOLOGICAL6 trials

Sponsors

Chongqing Precision Biotech Co., Ltd, Second Affiliated Hospital, School of Medicine, Zhejiang University

Conditions

Bile Duct CancerBreast CancerCholangiocarcinomaColon CancerColorectal CancerEsophageal CancerEsophagus CancerGastric Cancer

Phase 1

Safety and Efficacy of CEA-targeted CAR-T for CEA-positive Advanced Malignant Solid Tumors

CompletedNCT05538195

Chongqing Precision Biotech Co., LtdColon Cancer, Esophageal Cancer, Gastric Cancer +2

Start: 2022-06-07End: 2024-02-07Updated: 2026-07-10

CEA Targeting Chimeric Antigen Receptor T Lymphocytes (CAR-T) in the Treatment of CEA Positive Advanced Solid Tumors

RecruitingNCT06006390

Chongqing Precision Biotech Co., LtdBreast Cancer, Colon Cancer, Esophageal Cancer +4

Start: 2023-09-07End: 2026-08-31Target: 60Updated: 2024-08-09

A Clinical Trial Targeting CEA Chimeric Antigen Receptor T (CAR-T) for CEA Positive Advanced Malignant Solid Tumors

RecruitingNCT06043466

Chongqing Precision Biotech Co., LtdBile Duct Cancer, Breast Cancer, Colorectal Cancer +4

Start: 2023-08-11End: 2027-12-31Target: 30Updated: 2023-09-21

Clinical Study of CEA Targeting Chimeric Antigen Receptor T Lymphocytes（CAR-T） for CEA Positive Advanced Malignant Solid Tumors

RecruitingNCT06126406

Chongqing Precision Biotech Co., LtdBreast Cancer, Cholangiocarcinoma, Colon Cancer +5

Start: 2023-11-06End: 2026-12-31Target: 60Updated: 2023-11-13

CEA-Targeted CAR-T Therapy in CEA-Positive Advanced Solid Tumors

RecruitingNCT07179692

Chongqing Precision Biotech Co., LtdColon Cancer, Esophageal Cancer, Gastric Cancer +3

Start: 2025-09-12End: 2028-05-31Target: 108Updated: 2025-10-02

CEA CAR-T Therapy After Cytoreduction in Colorectal Cancer Patients With Peritoneal Metastases

RecruitingNCT07247396

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityPeritoneal Metastases From Colorectal Cancer

Start: 2025-11-03End: 2027-10-31Target: 12Updated: 2025-11-25