CDDP

DRUG3 trials

Sponsors

Merck Sharp & Dohme LLC, Huashan Hospital, National Cancer Center, Japan

Conditions

High-grade GliomasLocally Advanced Esophageal Squamous Cell CarcinomaSolid Tumors

Phase 1

A Dose Escalation Study of Adavosertib(MK1775) in Combination With 5-FU or 5-FU/CDDP in Patients With Advanced Solid Tumor (1775-005

TerminatedNCT01047007

Merck Sharp & Dohme LLCSolid Tumors

Start: 2010-01-18End: 2011-06-15Updated: 2023-09-21

A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal Carcinoma

CompletedNCT03914443

National Cancer Center, JapanLocally Advanced Esophageal Squamous Cell Carcinoma

Start: 2019-05-07End: 2025-03-31Updated: 2025-05-31

Phase 2

Efficacy and Tolerability of Cisplatin Plus Alternating Weekly Temozolomide in Recurrent High-grade Gliomas

CompletedNCT02263105

Huashan HospitalHigh-grade Gliomas

Start: 2014-10-31End: 2018-06-30Updated: 2018-07-17

Related Papers

199. THE CORRELATION BETWEEN HISTOPATHOLOGICAL RESPONSE OF NIVOLUMAB-CONTAINING NEOADJUVANT CHEMOTHERAPY AND IMMUNE CELL TYPES FOR LOCALLY ADVANCED ESOPHAGEAL SQUAMOUS CELL CARCINOMA

Diseases of the Esophagus2025-08-01

271. EFFICACY OF NEOADJUVANT CF OR DCF, FLOT PLUS NIVOLUMAB FOR RESECTABLE LOCALLY ADVANCED ESOPHAGEAL SQUAMOUS CELL CARCINOMA (JCOG1804E: FRONTIER)

Diseases of the Esophagus2024-09-01

FRONTiER: A feasibility trial of nivolumab with neoadjuvant CF or DCF, FLOT therapy for locally advanced esophageal carcinoma (JCOG1804E)—Primary safety and short-term efficacy results for cohort E.

Journal of Clinical Oncology2024-01-202 citations

FRONTiER: A feasibility trial of nivolumab with neoadjuvant CF or DCF, FLOT therapy for locally advanced esophageal carcinoma (JCOG1804E)—Short-term results for cohorts C and D.

Journal of Clinical Oncology2022-01-1922 citations

FRONTiER: A feasibility trial of nivolumab with neoadjuvant CF or DCF therapy for locally advanced esophageal carcinoma (JCOG1804E)—The short-term results of cohort A and B.

Journal of Clinical Oncology2021-01-2019 citations

A phase II, single-centre trial of neoadjuvant toripalimab plus chemotherapy in locally advanced esophageal squamous cell carcinoma

Journal of Thoracic Disease2020-11-0142 citations

Feasibility Study of Nivolumab as Neoadjuvant Chemotherapy for Locally Esophageal Carcinoma: FRONTiER (JCOG1804E)

Future Oncology2020-05-1267 citations