CD45RA-depleted peripheral blood mononuclear cells

BIOLOGICAL2 trials

Sponsors

Federal Research Institute of Pediatric Hematology, Oncology and Immunology

Conditions

Bone Marrow Failure SyndromesGraft vs Host DiseaseGraft-versus-Host DiseaseGvHDImmune Deficiency DiseaseLeukemiaLeukemia, Myeloid, AcuteLymphoma

Phase 1

Memory T-cell Infusion to Improve Immunity After TCR-alpha/Beta Depleted Hematopoietic Stem Cell Transplantation

CompletedNCT02337595

Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyBone Marrow Failure Syndromes, Graft vs Host Disease, Immune Deficiency Disease +3

Start: 2014-08-31End: 2016-01-31Updated: 2016-04-22

Phase 2

CD45RA Depleted T-cell Infusion for Prevention of Infections After TCRab/CD19-depleted Allo-HSCT

CompletedNCT02942173

Federal Research Institute of Pediatric Hematology, Oncology and ImmunologyGraft-versus-Host Disease, GvHD, Leukemia +3

Start: 2016-10-31End: 2020-08-21Updated: 2023-03-16