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CD-NP

DRUG8 trials

Sponsors

Nile Therapeutics, Mayo Clinic, John A. Schirger

Conditions

Acute Decompensated Heart FailureCongestive Heart FailureHeart FailureHeart Failure, CongestiveLeft Ventricular Assist DeviceLeft Ventricular InsufficiencyNatriuretic PeptideRenal Insufficiency

Phase 1

Safety and Pharmacodynamic Study of CD-NP
CompletedNCT00482937
Nile TherapeuticsHeart Failure, Congestive
Start: 2007-01-31End: 2007-05-31Updated: 2007-06-06
Safety Study of CD-NP in Heart Failure
CompletedNCT00557661
Nile TherapeuticsCongestive Heart Failure
Start: 2007-11-30End: 2008-12-31Updated: 2009-03-25
CD-NP in Subjects With Stable Chronic Heart Failure
CompletedNCT00620308
Mayo ClinicStable Chronic Heart Failure
Start: 2008-06-30End: 2012-02-29Updated: 2012-09-10
Effects of Chimeric Natriuretic Peptide Versus Placebo in Stable Heart Failure and Moderate Renal Dysfunction
WithdrawnNCT01407900
John A. SchirgerHeart Failure, Renal Insufficiency
Start: 2014-01-31End: 2014-02-28Updated: 2014-06-17
Safety Study of Chimeric Natriuretic Peptide(CD-NP) in Stable LVAD Patients
CompletedNCT01750905
Mayo ClinicLeft Ventricular Insufficiency
Start: 2013-04-30End: 2016-08-31Updated: 2016-08-30
CD-NP (Cenderitide) Therapy for the Preservation of Left Ventricular Function
CompletedNCT02071602
Mayo ClinicST Elevation (STEMI) Myocardial Infarction of Anterior Wall
Start: 2013-10-31End: 2018-11-30Updated: 2021-03-10
Subcu Administration of CD-NP in Heart Failure Patients With Left Ventricular Assist Device Support
WithdrawnNCT03091998
Mayo ClinicHeart Failure, Left Ventricular Assist Device, Natriuretic Peptide
Start: 2017-09-30End: 2020-05-01Updated: 2017-07-28

Phase 2

Study to Assess the Safety and Efficacy of CD-NP in the Treatment of Patients With Acute Decompensated Heart Failure
CompletedNCT00839007
Nile TherapeuticsAcute Decompensated Heart Failure
Start: 2009-06-30End: 2010-07-31Updated: 2010-09-17