CAZ104

DRUG3 trials

Sponsors

Pfizer

Conditions

HealthyHealthy Male and Female Japanese Volunteers

Phase 1

A Study to Assess the Safety, Tolerability and Pharmacokinetics of NXL104 Alone and in Combination With Ceftazidime Administered as Single and Repeated Intravenous Doses in Healthy Japanese Subjects

CompletedNCT01291602

PfizerHealthy Male and Female Japanese Volunteers

Start: 2011-02-28End: 2011-04-30Updated: 2017-09-01

Study to Assess the Concentration of Avibactam and Ceftazidime in Epithelial Lining Fluid and Plasma

CompletedNCT01395420

Start: 2011-08-31End: 2012-07-31Updated: 2017-09-01

A Study to Assess the Levels of Two Antibiotics in the Blood When Given Together and Separately

CompletedNCT01430910

Start: 2011-09-30End: 2012-10-31Updated: 2017-09-01

Related Papers

Population Pharmacokinetic Modelling of Ceftazidime and Avibactam in the Plasma and Epithelial Lining Fluid of Healthy Volunteers.

2018-09-0142 citations

Randomized pharmacokinetic and drug–drug interaction studies of ceftazidime, avibactam, and metronidazole in healthy subjects

Pharmacology Research & Perspectives2015-08-2542 citations

Phase 1 study assessing the steady-state concentration of ceftazidime and avibactam in plasma and epithelial lining fluid following two dosing regimens.

2015-07-01103 citations

Phase I study assessing the safety, tolerability, and pharmacokinetics of avibactam and ceftazidime-avibactam in healthy Japanese volunteers.

2015-04-2824 citations