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CART-EGFR-IL13Ra2 cells
DRUG
2 trials
Sponsors
University of Pennsylvania
Conditions
Glioblastoma
Phase 1
CART-EGFR-IL13Ra2 in EGFR Amplified Recurrent GBM
Active, not recruiting
NCT05168423
University of Pennsylvania
Glioblastoma
Start: 2023-02-24
End: 2039-12-19
Updated: 2026-04-13
CART-EGFR-IL13Ra2 in Newly Diagnosed GBM Following Initial Radiotherapy
Recruiting
NCT06973096
University of Pennsylvania
Glioblastoma
Start: 2025-07-18
End: 2042-07-01
Target: 9
Updated: 2026-05-11
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2025-06-01
24 citations
A phase 1 study of intracerebroventricular (ICV) delivery of bivalent chimeric antigen receptor (CAR) T-cells targeting EGFR and IL13Ra2 in patients with recurrent glioblastoma (rGBM).
Journal of Clinical Oncology
2025-05-28
4 citations
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2024-11-01
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Neuro-Oncology
2023-11-01
1 citations