Carotid endarterectomy (CEA)

PROCEDURE8 trials

Sponsors

Rutgers, The State University of New Jersey, University Ghent, Mayo Clinic, Xuanwu Hospital, Beijing, Shanghai Pudong Hospital

Conditions

AtherosclerosisCarotid Artery DiseasesCarotid Artery PlaqueCarotid Artery StenosisCarotid Endarterectomy (CEA) Surgical PatientsCarotid StenosisCerebral InfarctionMyocardial Infarction

Unknown Phase

Carotid Revascularization Endarterectomy Versus Stenting Trial

CompletedNCT00004732

Rutgers, The State University of New JerseyAtherosclerosis, Carotid Stenosis, Cerebral Infarction +2

Start: 2000-12-31End: 2016-12-31Updated: 2017-05-17

Carotid Endarterectomy Versus Carotid Artery Stenting? A Prospective Comparison of Neuropsychological Outcome in Patients With Carotid Stenosis.

CompletedNCT01337128

University GhentCarotid Stenosis

Start: 2011-04-30End: 2015-09-30Updated: 2021-12-01

Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis Trial

CompletedNCT02089217

Mayo ClinicCarotid Stenosis

Start: 2014-12-09End: 2025-09-12Updated: 2025-10-01

Carotid Revascularization for Radiation Induced Carotid Artery Stenosis

RecruitingNCT05134246

Xuanwu Hospital, BeijingRadiation-induced Carotid Artery Stenosis

Start: 2020-01-05End: 2027-12-31Target: 150Updated: 2025-03-03

SSPC Evaluation on Carotid Artery Stenosis After Endarterectomy

Shanghai Pudong HospitalCarotid Artery Diseases, Carotid Artery Plaque, Carotid Stenosis

Start: 2022-04-01End: 2023-11-30Target: 200Updated: 2022-05-10

Revascularization for Symptomatic Non-acute Carotid Artery Occlusion

RecruitingNCT06303414

Xuanwu Hospital, BeijingNon-acute Carotid Artery Occlusion

Start: 2016-06-17End: 2028-12-30Target: 1000Updated: 2024-03-12

Ocular Perfusion in Patients With Unilateral Carotid Artery Stenosis

RecruitingNCT06398223

Medical University of ViennaCarotid Artery Stenosis

Start: 2024-04-09End: 2026-05-02Target: 45Updated: 2024-05-03

Ultrasound Evaluation for Baxter VASCU-GUARD Vascular Patches Post-Endarterectomy and Complications Assessment

CompletedNCT07048067

The Methodist Hospital Research InstituteCarotid Endarterectomy (CEA) Surgical Patients

Start: 2023-01-01End: 2025-02-01Updated: 2025-07-02

Related Papers

Medical Management and Revascularization for Asymptomatic Carotid Stenosis.

2025-11-211 citations

Adapting to Evolving Technologies and Treatment Guidelines in a Procedural Trial: A Qualitative Review of the CREST-2 Experience.

2023-02-062 citations

Baseline Cognitive Impairment in Patients With Asymptomatic Carotid Stenosis in the CREST-2 Trial

Stroke2021-08-2656 citations

Non-Adherence to Antihypertensive Guidelines in Patients with Asymptomatic Carotid Stenosis.

2021-06-1810 citations

Absence of Consistent Sex Differences in Outcomes From Symptomatic Carotid Endarterectomy and Stenting Randomized Trials

Stroke2021-01-2515 citations

Management of Vascular Risk Factors in the Carotid Revascularization Endarterectomy Versus Stenting Trial (CREST)

UNC Libraries2020-11-05

Mitigating the effects of COVID-19 pandemic on controlling vascular risk factors among participants in a carotid stenosis trial

Journal of Stroke and Cerebrovascular Diseases2020-09-294 citations

Rationale, Design, and Implementation of Intensive Risk Factor Treatment in the CREST2 Trial

Stroke2020-09-2137 citations

Secular Trends in Procedural Stroke or Death Risks of Stenting Versus Endarterectomy for Symptomatic Carotid Stenosis.

2019-08-0511 citations

Who says "no" to participating in stroke clinical trials and why: an observational study from the Vancouver Stroke Program.

2019-05-3125 citations

Periprocedural Stroke and Myocardial Infarction as Risks for Long-Term Mortality in CREST

Circulation Cardiovascular Quality and Outcomes2018-11-0131 citations

Immediate and Delayed Procedural Stroke or Death in Stenting Versus Endarterectomy for Symptomatic Carotid Stenosis

Stroke2018-10-1536 citations

Challenge and Yield of Enrolling Racially and Ethnically Diverse Patient Populations in Low Event Rate Clinical Trials

Stroke2017-11-3019 citations

Safety of Simultaneous Coronary Artery Bypass Grafting and Carotid Endarterectomy Versus Isolated Coronary Artery Bypass Grafting

Stroke2017-09-1688 citations

Factors Associated With Time to Site Activation, Randomization, and Enrollment Performance in a Stroke Prevention Trial

Stroke2017-08-035 citations

Carotid revascularization and medical management for asymptomatic carotid stenosis: Protocol of the CREST-2 clinical trials

International Journal of Stroke2017-05-02204 citations

Early Endarterectomy Carries a Lower Procedural Risk Than Early Stenting in Patients With Symptomatic Stenosis of the Internal Carotid Artery

Stroke2017-04-2997 citations

Clinical need, design, and goals for the Carotid Revascularization and Medical Management for Asymptomatic Carotid Stenosis trial.

2017-03-0121 citations

An Observational Registry of Carotid Endarterectomy and Carotid Artery Stenting in Brazil: Study Protocol

JMIR Research Protocols2016-11-233 citations

Long-Term Results of Stenting versus Endarterectomy for Carotid-Artery Stenosis

New England Journal of Medicine2016-02-18707 citations

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