Carisbamate
Sponsors
Sk Life Science Inc., SK Life Science, Inc., Baylor College of Medicine
Conditions
Alcohol AbuseAlcohol DependenceComplex Partial SeizuresEpilepsies, PartialEpilepsyEpilepsy, Complex PartialEpilepsy, Partial, MotorEpilepsy, Simple Partial
Phase 1
Carisbamate as a Potential Treatment for Alcohol Dependence
CompletedNCT02435381
Start: 2013-02-28End: 2013-09-30Updated: 2021-03-02
Carisbamate in Adult & Pediatric Subjects With Lennox-Gastaut Syndrome
CompletedNCT03731715
Start: 2019-02-07End: 2022-06-29Updated: 2023-05-30
Carisbamate Safety Study in Adult and Pediatric Subjects With Lennox-Gastaut Syndrome
CompletedNCT04062981
Start: 2019-05-03End: 2022-12-14Updated: 2024-04-04
Bioavailability and Food Effect Study of 3 Types of Carisbamate
CompletedNCT04520360
Start: 2020-08-27End: 2021-10-06Updated: 2021-10-07
Phase 2
An Effectiveness and Safety Study With RWJ-333369 (Carisbamate) for the Study of Postherpetic Neuralgia (PHN).
CompletedNCT00492323
Start: 2007-03-31End: 2008-06-30Updated: 2018-05-01
A Proof of Concept Study of the Effectiveness of Carisbamate in the Treatment of Essential Tremor
CompletedNCT00524056
Start: 2007-08-31End: 2008-03-31Updated: 2013-01-24
Phase 3
Carisbamate Retention Study (CaReS): Comparative Study on the Long Term Effectiveness, Safety and Tolerability of Carisbamate Compared to Two Other Frequently Prescribed Anti-epileptic Drugs (AEDs) in Patients With Epilepsy.
TerminatedNCT00563459
Start: 2007-11-30End: 2010-04-30Updated: 2013-01-29
A Study of the Effectiveness, Safety, and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures.
CompletedNCT00740623
Start: 2009-01-31End: 2010-04-30Updated: 2013-01-24
An Open-Label Extension Study of the Safety and Tolerability of Carisbamate as Add-On Therapy in Patients With Partial Onset Seizures
CompletedNCT00744731
Start: 2009-01-31End: 2010-08-31Updated: 2013-06-18
An Open-Label Extension Study to Evaluate the Safety and Tolerability of RWJ 333369 as Adjunctive Therapy in Patients 16 Years and Older With Partial Onset Seizures.
CompletedNCT00991757
Start: 2007-02-28End: 2010-10-31Updated: 2013-06-18
Investigate Efficacy and Safety of Carisbamate as Adjunctive Treatment for Seizures Associated With LGS in Children and Adults
RecruitingNCT05219617
Start: 2022-04-28End: 2028-12-31Target: 252Updated: 2025-07-24
A Randomized, Double-blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of Carisbamate (YKP509) as Adjunctive Treatment for Seizures Associated with Lennox-Gastaut Syndrome in Children and Adults, with Optional Open- Label Extension
RecruitingCTIS2023-506616-41-00
Start: 2023-03-31Target: 92Updated: 2025-11-14