CAR-T cell

DRUG9 trials

Conditions

Acute Lymphoblastic LeukemiaAcute Myeloid LeukemiaAdvanced Breast CancerAutoimmune DiseasesB Cell LymphomaCarcinoma, HepatocellularColorectal Cancer MetastaticDiffuse Large B Cell Lymphoma

Early Phase 1

A Study of CAR-T Cells in Subjects with Autoimmune Diseases

Not yet recruitingNCT06762119

Zhejiang UniversityAutoimmune Diseases

Start: 2025-01-10End: 2027-11-15Target: 6Updated: 2025-01-07

A Study of CAR-T Cells in Subjects With Autoimmune Diseases

Not yet recruitingNCT07040917

Chinese PLA General HospitalAutoimmune Diseases

Start: 2025-09-30End: 2028-04-30Target: 12Updated: 2025-07-20

Phase 1

A Study of Chimeric Antigen Receptor T Cells Combined With Interventional Therapy in Advanced Liver Malignancy

NCT02959151

Shanghai GeneChem Co., Ltd.Carcinoma, Hepatocellular, Colorectal Cancer Metastatic, Pancreatic Cancer Metastatic

Start: 2016-07-31End: 2018-07-31Target: 20Updated: 2016-11-08

GPC3 Targeted CAR-T Cell Therapy in Advanced GPC3 Expressing Solid Tumor Malignancies

RecruitingNCT05003895

National Cancer Institute (NCI)Hepatocellular Cancer, Hepatocellular Carcinoma, Metastatic Hepatocellular Carcinoma

Start: 2021-12-08End: 2027-12-31Target: 38Updated: 2026-04-07

Treating Nectin-4-positive Advanced Breast Cancer with XKDCT293 (Nectin-4-CAR-T)

RecruitingNCT06724835

Shenzhen Celconta Life Science Co., Ltd.Advanced Breast Cancer

Start: 2024-03-11End: 2026-03-31Target: 18Updated: 2024-12-09

IOMAB-CAR-T Followed by CAR-T Cell Therapy in R/R DLBCL

RecruitingNCT06768905

University of Texas Southwestern Medical CenterDiffuse Large B Cell Lymphoma, Non Hodgkin Lymphoma

Start: 2025-04-25End: 2030-05-01Target: 30Updated: 2026-05-08

Efficacy and Safety of CD19CD20-CAR.p40-T in B-cell Lymphoma

RecruitingNCT07097207

Shenzhen University General HospitalRelapsed/Refractory B-cell Lymphoma

Start: 2023-10-01End: 2026-09-30Target: 20Updated: 2025-07-31

Efficacy and Safety of CD19-CAR.p40-T in Patients With Relapsed/Refractory CD19-Positive Hematologic Malignancies

RecruitingNCT07584889

Shenzhen University General HospitalAcute Lymphoblastic Leukemia, Acute Myeloid Leukemia, B Cell Lymphoma

Start: 2024-04-20End: 2029-04-19Target: 10Updated: 2026-05-13

Unknown Phase

A Study of CAR-T Cells in Subjects With Systemic Lupus Erythematosus

Not yet recruitingNCT06900764

Union Hospital, Tongji Medical College, Huazhong University of Science and TechnologySystemic Lupus Erythematosus (SLE)

Start: 2025-10-10End: 2027-12-20Target: 24Updated: 2025-07-17

Related Papers

On-target/off-tumor toxicities following infusion of low-affinity Nectin-4-specific CAR T cells.

2025-12-04

A phase I study of GPC3 targeted CAR-T cell therapy in advanced GPC3-expressing hepatocellular carcinoma (HCC).