Capecitabine Accord 500 mg film-coated tablets
Sponsors
Fondation Franc.Cancerologie Digestive, Astrazeneca AB, Bristol-Myers Squibb Services Unlimited Company, Exscientia AI Limited, Centre Hospitalier Universitaire De Dijon
Conditions
Advanced solid tumorsAmpullary adenocarcinomaBiliary tract cancerBiliary tract carcinomaColorectal liver metastasesIntrahepatic cholangiocarcinomaLocally Advanced Unresectable Esophageal Squamous Cell CarcinomaMMRp/ MSS colon cancer
Phase 1
A phase 1/2 open-label, multicenter study to assess the safety, pharmacokinetics and anti-tumor activity of GTAEXS617 in patients with advanced solid tumors
RecruitingCTIS2023-508227-13-00
Start: 2023-06-19Target: 112Updated: 2026-01-14
A Phase 1b Multicentre, Open-label, Modular, Dose-finding and Dose-expansion Study to Explore the Safety, Tolerability, Pharmacokinetics and Anti-tumour Activity of Trastuzumab Deruxtecan (T-DXd) in Combination with Other Anti-cancer Agents in Patients with Metastatic HER2-low Breast Cancer (DESTINY-Breast08)
Active, not recruitingCTIS2023-505690-33-00
Start: 2022-03-11Target: 12Updated: 2026-01-21
NEOadjuvant chemotherapy only compared with standard treatment for Locally Advanced Rectal cancer: a randomized phase II trial
Active, not recruitingCTIS2024-517748-76-00
Start: 2016-11-14Target: 124Updated: 2024-10-08
Hepatic arterial infusion versus intravenous oxaliplatin in a safety, feasibility, and pharmacokinetic study of liver-dominant malignancies – ARTEMIS OXYS-I trial
Not yet recruitingCTIS2026-527509-39-01
Target: 13Updated: 2026-10-07
Phase 2
PRODIGE 76-IMMUNOBILADJ: Capecitabine plus durvalumab or capecitabine alone as adjuvant therapy in patients with resected biliary tract carcinoma. A non-comparative randomized phase II study
CompletedCTIS2023-503807-27-00
End: 2023-08-29Target: 219Updated: 2023-07-07
Pan Tumor Study for Long-term Treatment of Cancer Patients Who Have Participated in BMS sponsored Trials Investigating Nivolumab and Other Cancer Therapies
RecruitingCTIS2023-506914-32-00
Start: 2020-05-05Target: 307Updated: 2026-01-19
A multicenter open-label randomized controlled prospective phase II study evaluating the efficacy of Selective Internal Radiation Therapy (Yttrium-90 glass microspheres) combined with Capecitabine in the neoadjuvant setting of Operable intrahepatic CHOlangiocarcinoma
RecruitingCTIS2024-516683-29-00
Start: 2022-02-04Target: 62Updated: 2025-05-13
A Phase 2, open label, randomized study of neoadjuvant dostarlimab plus CAPEOX versus CAPEOX in participants with previously untreated T4N0 or Stage III MMRp/ MSS colon cancer
RecruitingCTIS2024-513441-36-00
Start: 2024-11-27Target: 170Updated: 2025-12-18
Phase 3
A Phase III, Randomized, Double-Blind, Placebo Controlled, Multi-Center, International Study of Durvalumab Given Concurrently With Definitive Chemoradiation Therapy in Patients With Locally Advanced, Unresectable Esophageal Squamous Cell Carcinoma (KUNLUN).
Active, not recruitingCTIS2023-506413-22-00
Start: 2021-03-31Target: 48Updated: 2026-01-09
PRODIGE 98- AMPIRINOX : Randomized, multicenter, Phase III trial of adjuvant chemotherapy with modified FOLFIRINOX versus capecitabine or gemcitabine in patients with resected ampullary adenocarcinoma.
RecruitingCTIS2024-511070-68-01
Start: 2024-09-24Target: 294Updated: 2025-08-29
PembroLizumab Adjuvant in patients with early-stage Triple NEgaTive breast cancer with residual disease after neoadjuvant pembrolizumab plus chemotherapy – the multicenter, randomized phase III, pragmatic PLANET trial
Not yet recruitingCTIS2025-524229-41-00
Target: 1000Updated: 2026-04-01
First adjuvant trial in locally resected aggressive pancreatic neuroendocrine tumors: a randomized phase III investigating the efficacy of systemic chemotherapy (ADJUPANET)
Not yet recruitingCTIS2025-523593-16-00
Target: 504Updated: 2026-06-10