Canagliflozin 300 mg
Sponsors
Janssen Research & Development, LLC, Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Janssen-Cilag International NV, Lexicon Pharmaceuticals, Johnson & Johnson Private Limited
Conditions
CKD (Chronic Kidney Disease) Stage 5DDiabetes Mellitus, Type 1Diabetes Mellitus, Type 2ESRDHealthyHealthy Subjects
Phase 1
A Pharmacokinetic and Pharmacodynamic Study to Determine Blood Levels of JNJ-28431754 (Canagliflozin) in Patients With Type 2 Diabetes Mellitus
CompletedNCT01128985
Start: 2010-03-31End: 2010-07-31Updated: 2013-05-29
A Single and Multiple Dose Study of Canagliflozin in Healthy Volunteers
CompletedNCT01281579
Start: 2011-01-31End: 2011-04-30Updated: 2012-11-30
Effects of Canagliflozin on C-peptide Clearance in Healthy Volunteers
CompletedNCT01665638
Start: 2012-09-30End: 2012-10-31Updated: 2013-06-07
Study to Evaluate the Effect of Single Doses of LX4211 and Canagliflozin on Intestinal Glucose Absorption in Healthy Adult Subjects
CompletedNCT01916863
Start: 2013-08-31Updated: 2013-10-30
A Study to Evaluate the Pharmacokinetics, Pharmacodynamics and Safety of Canagliflozin in Older Children and Adolescents With Type 2 Diabetes Mellitus
CompletedNCT02000700
Start: 2014-03-31End: 2016-04-30Updated: 2017-03-03
Phase 2
A Study of Effects of Canagliflozin as Add-on Therapy to Insulin in the Treatment of Participants With Type 1 Diabetes Mellitus (T1DM)
CompletedNCT02139943
Start: 2014-05-31End: 2015-06-30Updated: 2016-07-18
Effect of Canagliflozin on Ultrafiltration & Fibrosis in Patients on Peritoneal Dialysis
RecruitingNCT06913647
Start: 2026-02-01End: 2028-12-31Target: 30Updated: 2026-03-16
Phase 3
A Safety and Efficacy Study of Canagliflozin in Older Patients (55 to 80 Years of Age) With Type 2 Diabetes Mellitus
CompletedNCT01106651
Start: 2010-06-30End: 2013-05-31Updated: 2014-11-04
The CANTATA-D2 Trial (CANagliflozin Treatment And Trial Analysis - DPP-4 Inhibitor Second Comparator Trial)
CompletedNCT01137812
Start: 2010-07-31End: 2012-03-31Updated: 2015-01-15
A Study to Evaluate the Effectiveness, Safety, and Tolerability of Canagliflozin in Combination With Metformin in the Treatment of Patients With Type 2 Diabetes Mellitus With Inadequate Glycemic Control With Diet and Exercise
CompletedNCT01809327
Start: 2013-06-04End: 2014-12-02Updated: 2017-07-11
A Study to Investigate the Efficacy and Safety of Canagliflozin in Children and Adolescents (>=10 to <18 Years) With Type 2 Diabetes Mellitus
CompletedNCT03170518
Start: 2017-07-21End: 2023-09-20Updated: 2025-04-25