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Calfactant

DRUG6 trials

Sponsors

University of Pittsburgh, Pneuma Pharmaceuticals Incorporated, Milton S. Hershey Medical Center, University of Missouri-Columbia, University of Wisconsin, Madison

Conditions

Acute Lung InjuryCystic FibrosisInvasive Mechanical VentilationRespiratory Distress SyndromeRespiratory Distress Syndrome (RDS)Respiratory Distress Syndrome in Premature InfantsRespiratory Distress Syndrome, AdultSevere Respiratory Distress Syndrome

Phase 1

Little Lungs Study
Not yet recruitingNCT06855043
University of Wisconsin, MadisonInvasive Mechanical Ventilation, Severe Respiratory Distress Syndrome
Start: 2026-09-01End: 2029-03-01Target: 24Updated: 2026-01-27

Phase 2

CALIPSO: Calfactant for Acute Lung Injury in Pediatric Stem Cell Transplant and Oncology Patients
CompletedNCT00999713
Milton S. Hershey Medical CenterAcute Lung Injury
Start: 2010-06-30End: 2015-10-31Updated: 2018-03-16

Phase 3

Calfactant for Direct Acute Respiratory Distress Syndrome
TerminatedNCT00682500
Pneuma Pharmaceuticals IncorporatedRespiratory Distress Syndrome, Adult
Start: 2008-05-31End: 2011-02-28Updated: 2012-07-24

Phase 4

Calfactant vs Poractant Alfa Using a Less Invasive Technique in Preterm Infants With Respiratory Distress Syndrome
RecruitingNCT07350018
Uludag UniversityRespiratory Distress Syndrome in Premature Infants, Respiratory Distress Syndrome (RDS), Surfactant
Start: 2026-01-20End: 2027-02-20Target: 234Updated: 2026-04-28

Unknown Phase

Self-dispersing Liquids as Aerosol Drug Carriers
CompletedNCT00628134
University of PittsburghCystic Fibrosis
Start: 2008-03-31End: 2009-08-31Updated: 2017-08-24
Comparison of Curosurf and Infasurf in the Treatment of Preterm Infants With Respiratory Distress Syndrome
CompletedNCT02834624
University of Missouri-ColumbiaRespiratory Distress Syndrome
Start: 2013-07-31End: 2015-07-31Updated: 2017-06-06

Related Papers

The Adult Calfactant in Acute Respiratory Distress Syndrome Trial.
2015-08-0159 citations