CALCIUM FOLINATE PENTAHYDRATE
Sponsors
Charite Universitaetsmedizin Berlin KöR, National Cancer Institute, AIO-Studien gGmbH, Heidelberg University
Conditions
locally advanced rectal cancermetastatic colorectal cancerstage III colon adenocarcinoma with deficient MMR
Phase 3
Randomized trial of standard chemotherapy alone or combined with atezolizumab as adjuvant therapy for patients with stage III colon cancer and deficient DNA mismatch repair (ATOMIC)
Not yet recruitingCTIS2024-517269-18-00
Target: 28Updated: 2025-10-17
ACO/ARO/AIO-18.2
Preoperative FOLFOX versus postoperative risk-adapted chemotherapy in patients with locally advanced rectal cancer and low risk for local failure:
A randomized phase III trial of the German Rectal Cancer Study Group
RecruitingCTIS2024-518077-34-00
Start: 2020-09-30Target: 550Updated: 2025-12-22
Post-resection/ ablation chemotherapy in patients with metastatic colorectal cancer (FIRE-9 - PORT / AIO-KRK-0418).
Prospective, randomized, open, multicenter Phase III trial to investigate the efficacy of active post-resection/ ablation therapy in patients with metastatic colorectal cancer.
RecruitingCTIS2024-512174-10-00
Start: 2021-11-11Target: 507Updated: 2025-09-04