Calcium Folinate 10 mg/ml Solution for injection or infusion

DRUG2 trials

Sponsors

Academisch Ziekenhuis Leiden, Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)

Conditions

Metastatic Colorectal CancerPatients with colorectal peritoneal metastases with a PCI-score of 1-20

Phase 2

Neo-adjuvant intraperitoneal chemotherapy (irinotecan) and systemic chemotherapy (mFOLFOX4-bevacizumab) prior to CRS-HIPEC for patients with isolated resectable colorectal peritoneal metastases: a multicentre, phase II trial (INTERACT-PLUS)

Not yet recruitingCTIS2024-512318-16-00

Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)Patients with colorectal peritoneal metastases with a PCI-score of 1-20

Target: 40Updated: 2026-01-02

Phase 3

DOSAgE study: A multicenter randomized phase III trial of DOSe-reduced Chemotherapy for Advanced Colorectal Cancer in Older patients

RecruitingCTIS2023-506115-17-00

Academisch Ziekenhuis LeidenMetastatic Colorectal Cancer

Start: 2024-10-14Target: 587Updated: 2025-03-31