Calcium Folinate 10 mg/ml Injection
Sponsors
Pfizer Inc., Catharina Ziekenhuis Stichting, Astellas Pharma Global Development Inc.
Conditions
Advanced cancer of the stomach or the gastroesophageal junctionColorectal cancer (BRAF V600E-mutant mCRC)Locally advanced rectal cancerLocally recurrent rectal cancer
Phase 2
Neo-adjuvant FOLFOXIRI and chemoradiotherapy for high risk (“ugly”) locally advanced rectal cancer.
Active, not recruitingCTIS2023-509758-74-00
Start: 2021-07-21Target: 128Updated: 2024-03-25
A Phase 2 Study of Zolbetuximab (IMAB362) as Monotherapy and in Combination with Chemotherapy and/or Immunotherapy in Subjects with Metastatic or Locally Advanced Unresectable Gastric or Gastroesophageal Junction (GEJ) Adenocarcinoma and Locoregional Gastric or GEJ Adenocarcinoma Whose Tumors are Claudin (CLDN) 18.2 Positive.
Active, not recruitingCTIS2024-511649-21-00
Start: 2018-08-01Target: 48Updated: 2026-01-23
Phase 3
C4221015 - AN OPEN-LABEL, MULTICENTER, RANDOMIZED PHASE 3 STUDY OF FIRST LINE ENCORAFENIB PLUS CETUXIMAB WITH OR WITHOUT CHEMOTHERAPY
VERSUS STANDARD OF CARE THERAPY WITH A SAFETY LEAD-IN OF ENCORAFENIB AND CETUXIMAB PLUS CHEMOTHERAPY IN PARTICIPANTS WITH METASTATIC BRAF V600E MUTANT COLORECTAL CANCER
Active, not recruitingCTIS2023-509405-77-00
Start: 2021-02-16Target: 300Updated: 2026-01-26
Multicentre, open-label, randomized, controlled, parallel arms clinical trial of induction chemotherapy followed by chemoradiotherapy versus chemoradiotherapy alone as neoadjuvant treatment for locally recurrent rectal cancer (PelvEx II)
RecruitingCTIS2024-512526-28-00
Start: 2020-10-28Target: 364Updated: 2026-01-19