Calcifediol

DRUG10 trials

Conditions

Acute Kidney InjuryAsthma, BronchialCOVID-19Critically IllFat MalabsorptionMyocardial InfarctionOsteopenia/OsteoporosisPatients with diagnosis of Pulmonary Arterial Hypertension of the following types according to 2022 ERS/ESC guidelines: idiopathic

Early Phase 1

25-Hydroxyvitamin D Pharmacokinetic Study

CompletedNCT03401541

Boston UniversityFat Malabsorption, Vitamin D Deficiency

Start: 2018-10-01End: 2019-11-01Updated: 2020-06-04

Phase 2

To Test the Effect of Calcifediol Hy.D Supplementation on Muscle Function and Bone Quality in Younger Postmenopausal Women With Osteopenia

CompletedNCT02527668

DSM Nutritional Products, Inc.Osteopenia/Osteoporosis

Start: 2015-09-30End: 2018-12-31Target: 150Updated: 2019-04-30

Activated Vitamin D for the Prevention and Treatment of Acute Kidney Injury

CompletedNCT02962102

David LeafAcute Kidney Injury, Critically Ill

Start: 2017-04-03End: 2020-08-06Updated: 2025-09-29

Phase 3

Effect of Vitamin D on Ventricular Remodeling in Patients With Acute Myocardial Infarction (VITDAMI)

CompletedNCT02548364

Instituto de Investigación Sanitaria de la Fundación Jiménez DíazMyocardial Infarction

Start: 2015-10-31End: 2023-05-31Updated: 2023-10-03

Phase 4

Efficacy and Safety of Paricalcitol in the Reduction of Secondary Hyperparathyroidism After Kidney Transplantation.

CompletedNCT01939977

Fundación SenefroSecondary Hyperparathyroidism Due to Renal Causes

Start: 2014-01-31End: 2015-12-31Updated: 2018-11-19

Efficacy of Calcifediol Supplementation in Asthma Control in Asthmatic Patients With Vitamin D Deficiency (ACViD)

CompletedNCT02805907

MurciaSaludAsthma, Bronchial

Start: 2016-06-30End: 2017-01-31Updated: 2017-06-16

MULTICENTER, RANDOMIZED, BLIND AND CONTROLLED CLINICAL TRIAL TO EVALUATE THE EFFICACY AND SAFETY OF XXXXXX IN THE CORRECTION OF 25(OH)D DEFICIT IN SUBJECTS WITH SEVERE VITAMIN D DEFICIENCY, COMPARED TO XXXXXX. DTREAT STUDY.

RecruitingCTIS2024-514528-17-00

Itf Research Pharma S.L.Severe vitamin D deficiency

Start: 2025-09-15Target: 120Updated: 2025-12-26

REstoration with calcifediol of VItamin D deficiency in pulmonary Arterial Hypertension patients (REVIDAH study)

Not yet recruitingCTIS2025-521694-14-00

Consorci Mar Parc De Salut De Barcelonadrug- and toxin-induced PAH or associated to connective tissues disease, hereditary, Patients with diagnosis of Pulmonary Arterial Hypertension of the following types according to 2022 ERS/ESC guidelines: idiopathic

Target: 102Updated: 2025-09-02

Unknown Phase

Calcifediol in the Treatment of COVID 19

CompletedNCT05819918

Maimónides Biomedical Research Institute of CórdobaCOVID-19

Start: 2022-04-01End: 2023-04-17Updated: 2023-04-28

Calcifediol in the Treatment of SARS-CoV-2 Disease (COVID-19).

CompletedNCT06279910

Complejo Hospitalario Universitario de AlbaceteSARS-CoV 2 Pneumonia

Start: 2024-02-21End: 2024-04-25Updated: 2025-06-05

JCI Insight2025-09-09

ALBACOVIDIOL Study: Effect of Calcifediol Treatment on Mortality in Patients Hospitalized for COVID-19: A Retrospective Analysis

Nutrients2025-06-10

Effect of calcifediol and cholecalciferol on muscle function in postmenopausal women: a randomized controlled trial

Osteoporosis International2025-04-09

Latent Class Analysis Reveals, in patient profiles, COVID-19-related better prognosis by calcifediol treatment than glucocorticoids.

2024-08-311 citations

Effect of vitamin D<sub>3</sub> vs. calcifediol on VDR concentration and fiber size in skeletal muscle.

2022-11-164 citations

A pilot-randomized, double-blind crossover trial to evaluate the pharmacokinetics of orally administered 25-hydroxyvitamin D3 and vitamin D3 in healthy adults with differing BMI and in adults with intestinal malabsorption.

2021-09-0122 citations

Effect of vitamin D supplementation on asthma control in patients with vitamin D deficiency: the ACVID randomised clinical trial

Thorax2020-11-0541 citations

TO020SHOULD WE DISCONTINUE CYCLOSPORIN OR STEROIDS IN RENAL TRANSPLANTATION? FIVE YEAR OUTCOME RESULTS OF THE CISTCERT TRIAL

Nephrology Dialysis Transplantation2017-05-01

TO019CONTROLLED RANDOMIZED STUDY COMPARING PARICALCITOL WITH CALCIFEDIOL FOR TREATING HYPERPARATHYROIDISM IN KIDNEY ALLOGRAFT RECIPIENTS

Nephrology Dialysis Transplantation2017-05-01

Design and rationale of a multicentre, randomised, double-blind, placebo-controlled clinical trial to evaluate the effect of vitamin D on ventricular remodelling in patients with anterior myocardial infarction: the VITamin D in Acute Myocardial Infarction (VITDAMI) trial

BMJ Open2016-08-019 citations