Cadazolid

DRUG5 trials

Sponsors

Actelion

Conditions

Clostridium Difficile Infection

Phase 1

Study to Investigate the Pharmacokinetics and Safety of Cadazolid in Patients With Clostridium Difficile Infection

CompletedNCT02053181

ActelionClostridium Difficile Infection

Start: 2012-08-31End: 2012-09-30Updated: 2014-02-03

Phase 2

Efficacy, Safety and Tolerability of Cadazolid in Subjects With Clostridium Difficile Associated Diarrhea (CDAD)

CompletedNCT01222702

ActelionClostridium Difficile Infection

Start: 2011-01-25End: 2012-11-12Updated: 2017-06-14

Comparison of Cadazolid Versus Vancomycin in Children With Clostridium Difficile-associated Diarrhea (CDAD)

TerminatedNCT03105479

ActelionClostridium Difficile Infection

Start: 2017-04-14End: 2018-04-17Updated: 2025-07-08

Phase 3

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile-associated Diarrhea

CompletedNCT01983683

ActelionClostridium Difficile Infection

Start: 2013-12-12End: 2017-05-02Updated: 2025-02-04

Efficacy and Safety of Cadazolid Versus Vancomycin in Subjects With Clostridium Difficile - Associated Diarrhea

CompletedNCT01987895

ActelionClostridium Difficile Infection

Start: 2014-03-27End: 2017-03-24Updated: 2025-02-04

Related Papers

Clostridium difficile Infection-Daily Symptoms (CDI-DaySyms™) questionnaire: psychometric characteristics and responder thresholds.

2019-05-034 citations

Cadazolid for the treatment of Clostridium difficile infection: results of two double-blind, placebo-controlled, non-inferiority, randomised phase 3 trials.

2019-01-2944 citations

The CDI-DaySyms: Content Development of a New Patient-Reported Outcome Questionnaire for Symptoms of Clostridium difficile Infection.

2017-11-078 citations

The Clostridium difficile Infection – Daily Symptoms (CDI-DaySyms™) Patient-Reported Outcome (PRO) Questionnaire: Final Validation and Responder Thresholds

Open Forum Infectious Diseases2017-01-012 citations

Susceptibility of Clostridium difficile isolates from a Phase 2 clinical trial of cadazolid and vancomycin in C. difficile infection.

2015-10-0324 citations

Minimal systemic and high faecal exposure to cadazolid in patients with severe Clostridium difficile infection.

2015-09-0310 citations

Multicenter, Double-Blind, Randomized, Phase 2 Study Evaluating the Novel Antibiotic Cadazolid in Patients with Clostridium difficile Infection

Antimicrobial Agents and Chemotherapy2015-07-2870 citations