C1-inhibitor

DRUG4 trials

Sponsors

TSI, LLC, Universitaire Ziekenhuizen KU Leuven, T. van der Poll, Academisch Medisch Centrum

Conditions

Acute Ischemic StrokeAsthmaReperfusion Injury

Early Phase 1

Research Into the Effect of a Clot-dissolving Agent and Its Inhibitor

TerminatedNCT01694381

TSI, LLCAcute Ischemic Stroke

Start: 2012-09-30End: 2012-10-31Updated: 2021-01-19

Phase 2

Combined Drug Approach to Prevent Ischemia-reperfusion Injury During Transplantation of Livers (CAPITL)

CompletedNCT02251041

Universitaire Ziekenhuizen KU LeuvenReperfusion Injury

Start: 2014-09-30End: 2019-08-31Updated: 2024-08-23

Phase 4

C1-inhibitor in Allergic ASThma Patients

TerminatedNCT03051698

T. van der PollAsthma

Start: 2016-11-16End: 2019-10-23Updated: 2020-06-24

Unknown Phase

Effect of Intravenous Administration of C1-inhibitor on Inflammation and Coagulation after Bronchial Instillation of House Dust Mite Allergen and Lipopolysaccharide in Allergic Asthma Patients

Active, not recruitingNL-OMON47623

Academisch Medisch CentrumAsthma

Start: 2016-11-15Target: 60Updated: 2024-02-28

Related Papers

Effect of the gut microbiota-derived tryptophan metabolite indole-3-acetic acid in pneumonia

Nature Communications2025-09-292 citations

Effect of a Combined Drug Approach on the Severity of Ischemia-Reperfusion Injury During Liver Transplant

JAMA Network Open2023-02-2811 citations