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C1 Esterase Inhibitor
DRUG
4 trials
Sponsors
CSL Behring
, Stanley Jordan, MD
, Cedars-Sinai Medical Center
Conditions
Delayed Graft Function
End Stage Renal Disease
Hereditary Angioedema
Ischemic Reperfusion Injury
Kidney Failure
Kidney Transplantation
Phase 1
Safety & Tolerability of Berinert® (C1 Inhibitor) Therapy to Prevent Rejection
Completed
NCT01134510
Stanley Jordan, MD
Kidney Transplantation
Start: 2011-08-31
End: 2013-11-30
Updated: 2017-03-21
C1INH Inhibitor Preoperative and Post Kidney Transplant to Prevent DGF & IRI
Completed
NCT02134314
Cedars-Sinai Medical Center
Delayed Graft Function, End Stage Renal Disease, Ischemic Reperfusion Injury +1
Start: 2014-09-30
End: 2017-03-13
Updated: 2018-06-25
Phase 2
Human C1 Esterase Inhibitor (C1-INH) in Subjects With Acute Abdominal or Facial Hereditary Angioedema (HAE) Attacks
Completed
NCT00168103
CSL Behring
Hereditary Angioedema
Start: 2005-06-30
End: 2007-12-31
Updated: 2015-03-31
Phase 3
C1 Esterase Inhibitor in Hereditary Angioedema (HAE)(Extension Study)
Completed
NCT00292981
CSL Behring
Hereditary Angioedema
Start: 2005-08-31
End: 2010-05-31
Updated: 2015-05-07
Related Papers
Three-Year Outcomes of a Randomized, Double-Blind, Placebo-Controlled Study Assessing Safety and Efficacy of C1 Esterase Inhibitor for Prevention of Delayed Graft Function in Deceased Donor Kidney Transplant Recipients.
2019-12-16
49 citations
A Phase I/II Placebo-Controlled Trial of C1 Inhibitor for Prevention of Antibody-Mediated Rejection in HLA Sensitized Patients.
Transplantation
2014-07-01
5 citations
Effect of time to treatment on response to C1 esterase inhibitor concentrate for hereditary angioedema attacks.
2013-07-16
36 citations
Treatment response after repeated administration of C1 esterase inhibitor for successive acute hereditary angioedema attacks.
2012-07-01
11 citations