Butylphthalide

DRUG9 trials

Conditions

Acute Ischemic StrokeBrain InfarctionBrain IschemiaCardiovascular DiseasesCentral Nervous System DiseasesCerebral InfarctionCerebral Small Vessel DiseasesCognitive Impairment

Phase 3

Butylphthalide for Preventing Restenosis After Intracranial and Extracranial Artery Stenting

CompletedNCT01405248

Jinling Hospital, ChinaRestenosis

Start: 2011-07-31End: 2014-01-31Updated: 2015-10-26

Efficacy and Safety of Butylphthalide for Acute Ischemic Stroke Patients Receiving Intravenous Thrombolysis or Endovascular Treatment

CompletedNCT03539445

Beijing Tiantan HospitalAcute Ischemic Stroke

Start: 2018-07-01End: 2022-07-31Updated: 2022-08-05

A Randomized Controlled Trial on the Efficacy and Safety of Butylphthalide in Reducing Myocardial Infarction Size and Improving Outcomes in STEMI Patients After Primary PCI

Not yet recruitingNCT06704685

Xiangya Hospital of Central South UniversityST-segment Elevation Myocardial Infarction (STEMI)

Start: 2024-12-01End: 2025-12-31Target: 40Updated: 2024-11-26

Butylphthalide for Long-term Efficacy in Minor Stroke Study

Not yet recruitingNCT07230587

Peking Union Medical College HospitalIschemic Stroke, Minor Stroke

Start: 2025-12-01End: 2028-10-01Target: 1200Updated: 2025-11-17

Isosorbide Mononitrate and Butylphthalide to Reduce the Risk of Disability in Patients With Acute Lacunar Stroke (IMPACT)

Not yet recruitingNCT07252544

Beijing Tiantan HospitalCerebral Small Vessel Diseases, Stroke, Acute Ischemic, Stroke, Lacunar

Start: 2025-12-01End: 2028-02-29Target: 3156Updated: 2025-11-26

Phase 4

For Patients With Ischemic Stroke, Clinically Study the Effectiveness and Safety of Butylphthalide.

RecruitingNCT05068349

Qianfoshan HospitalBrain Infarction, Brain Ischemia, Central Nervous System Diseases +4

Start: 2022-05-07End: 2025-12-31Target: 300Updated: 2024-04-09

Butylphthalide for Cognitive Impairment in Elderly Patients With Focal Epilepsy

RecruitingNCT07193277

First Affiliated Hospital of Wenzhou Medical UniversityCognitive Impairment, Focal Epilepsy

Start: 2025-09-01End: 2028-09-01Target: 220Updated: 2025-09-25

Unknown Phase

Using Real-world Evidence to Analyze the Clinical Effects and Adverse Events of Butylphthalide in Stroke Patients

CompletedNCT05086874

Xin HuangBrain Infarction, Brain Ischemia, Cardiovascular Diseases +5

Start: 2022-05-07End: 2023-03-01Updated: 2024-04-09

Efficacy of Butylphthalide on Symptomatic Atherosclerotic Stenosis in Middle Cerebral Artery

Not yet recruitingNCT06331494

First Affiliated Hospital, Sun Yat-Sen UniversityIntracranial Atherosclerosis, Ischemic Stroke, Acute

Start: 2024-03-15End: 2026-08-31Target: 140Updated: 2024-03-26

Related Papers

Efficacy and Safety of Butylphthalide in Patients With Acute Ischemic Stroke

JAMA Neurology2023-06-26110 citations

Abstract 90: Butylphthalide Improves Functional Outcome In Patients With Acute Ischemic Stroke Receiving Intravenous Thrombolysis And/or Endovascular Treatment In Comparison To Placebo

Stroke2023-02-01

Efficacy and safety of butylphthalide for patients who had acute ischaemic stroke receiving intravenous thrombolysis or endovascular treatment (BAST trial): study protocol for a randomised placebo-controlled trial

BMJ Open2021-05-0112 citations