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Bupropion XL

DRUG8 trials

Sponsors

GlaxoSmithKline, St. Luke's-Roosevelt Hospital Center, University Health Network, Toronto, University of California, Los Angeles, University of British Columbia

Conditions

Bipolar I DisorderCocaine DependenceDepressionDepressive Disorder, MajorDysthymic DisorderMajor DepressionMajor Depressive DisorderSubstance Abuse

Phase 2

Bupropion-Enhanced Contingency Management (CM) for Cocaine Dependence
CompletedNCT02111798
Johns Hopkins UniversityCocaine Dependence, Substance Abuse
Start: 2014-07-31End: 2021-01-31Updated: 2025-02-27

Phase 3

Major Depressive Disorder In The Elderly
CompletedNCT00093288
GlaxoSmithKlineDepressive Disorder, Major
Start: 2004-06-30End: 2005-10-31Target: 364Updated: 2013-09-02
Memory Functioning and Antidepressant Treatment
CompletedNCT00296933
University Health Network, TorontoDepression, Major Depressive Disorder
Start: 2005-12-31Target: 60Updated: 2009-02-17
Mood Stabilizer (MS)+ Antidepressant vs MS + Placebo in Maintenance of Bipolar Disorder.
TerminatedNCT00958633
University of British ColumbiaBipolar I Disorder
Start: 2010-11-30End: 2020-05-20Updated: 2025-05-15

Phase 4

Wellbutrin XL for Dysthymic Disorder
CompletedNCT00225251
St. Luke's-Roosevelt Hospital CenterDysthymic Disorder
Start: 2004-11-30End: 2008-06-30Updated: 2015-11-26
Personalized Indicators for Predicting Response to SSRI Treatment in Major Depression (The PRISE-MD Study)
CompletedNCT00917059
University of California, Los AngelesDepression
Start: 2009-05-31End: 2012-05-31Updated: 2013-02-06
Connectivity Affecting the Antidepressant REsponse Study
CompletedNCT02332291
Vanderbilt University Medical CenterMajor Depressive Disorder
Start: 2015-04-30End: 2020-08-31Updated: 2021-09-21
Bupropion Versus Escitalopram on Reward Circuitry and Motivational Deficits
CompletedNCT04352101
Emory UniversityMajor Depression
Start: 2020-09-23End: 2022-07-25Updated: 2023-12-29

Related Papers

Duration of Adjunctive Antidepressant Maintenance in Bipolar I Depression
New England Journal of Medicine2023-08-0231 citations
Bupropion Slow Release vs Placebo With Adaptive Incentives for Cocaine Use Disorder in Persons Receiving Methadone for Opioid Use Disorder
JAMA Network Open2023-03-153 citations
Influences of resting-state intrinsic functional brain connectivity on the antidepressant treatment response in late-life depression
Psychological Medicine2022-12-0911 citations