FindTrial
Sign In

Buprenorphine-Naloxone

DRUG6 trials

Sponsors

University of Oslo, NYU Langone Health, University of Minnesota, Didier Jutras Aswad, Virginia Commonwealth University

Conditions

AnalgesicsChronic PainDrug InteractionOpioid DependenceOpioid Use Disorder

Phase 1

Drug-drug Interaction Study of Lemborexant as an Adjunctive Treatment for Buprenorphine/Naloxone for Opioid Use Disorder
CompletedNCT04818086
Virginia Commonwealth UniversityAnalgesics, Drug Interaction, Opioid Use Disorder
Start: 2021-05-03End: 2023-04-20Updated: 2024-11-13

Phase 2

Veterans' Pain Care Organizational Improvement Comparative Effectiveness Study
CompletedNCT03026790
University of MinnesotaChronic Pain
Start: 2017-10-19End: 2022-10-30Updated: 2023-06-05

Phase 3

Naltrexone vs Buprenorphine-Naloxone for Opioid Dependence in Norway
CompletedNCT01717963
University of OsloOpioid Dependence
Start: 2012-10-31End: 2018-04-30Updated: 2018-10-11

Phase 4

Extended-Release Naltrexone vs. Buprenorphine for Opioid Treatment
CompletedNCT02032433
NYU Langone HealthOpioid Use Disorder
Start: 2014-01-29End: 2017-01-31Updated: 2020-08-13
A Pragmatic Randomized Control Trial Comparing Models of Care in the Management of Prescription Opioid Misuse
CompletedNCT03033732
Didier Jutras AswadOpioid Use Disorder
Start: 2017-10-02End: 2020-12-31Updated: 2021-06-16
Low-dose Buprenorphine Initiation for Opioid Use Disorder
RecruitingNCT05450718
Montefiore Medical CenterOpioid Use Disorder
Start: 2024-11-11End: 2027-06-30Target: 70Updated: 2025-09-17

Related Papers

MiBUP: A pilot randomized controlled trial of low-dose initiation of buprenorphine for opioid use disorder: Design and rationale.
2026-01-05
Concordance Between Urine Drug Screening and Self-Reported Use in the Context of a Pragmatic Randomized-Controlled Trial in People with <i>Prescription-Type</i> Opioid Use Disorder: Concordance entre le dépistage de drogues dans l’urine et l’usage autodéclaré dans le contexte d’un essai pragmatique contrôlé à répartition aléatoire chez des personnes présentant un trouble lié à l'usage d’opioïdes vendus sur ordonnance
The Canadian Journal of Psychiatry2025-08-28
Suicidal ideation in adults with opioid use disorder treated with buprenorphine-naloxone versus extended-release naltrexone
The American Journal of Drug and Alcohol Abuse2025-07-11
Buprenorphine, Pain, and Opioid Use in Patients Taking High-Dose Long-Term Opioids: A Randomized Clinical Trial.
2025-04-015 citations
Changes in mental health during long-term treatment with extended-release naltrexone: A 3-year clinical study of opioid dependent individuals
Contemporary Clinical Trials2025-02-211 citations
Opioid consumption frequency and its associations with potential life problems during opioid agonist treatment in individuals with prescription-type opioid use disorder: exploratory results from the OPTIMA Study.
2025-02-08
Care Models to Improve Pain and Reduce Opioids Among Patients Prescribed Long-Term Opioid Therapy
2024-12-14
Care Models to Improve Pain and Reduce Opioids Among Patients Prescribed Long-Term Opioid Therapy
JAMA Internal Medicine2024-12-0914 citations
Characterising methamphetamine/amphetamine use among opioid agonist therapy‐seeking adults with prescription‐type opioid use disorder in Canada
Drug and Alcohol Review2024-05-094 citations
Impact of Depressive Symptom Severity on Buprenorphine/Naloxone and Methadone Outcomes in People With Prescription-Type Opioid Use Disorder: Results From a Pragmatic Randomized Controlled Trial
Journal of Dual Diagnosis2024-04-052 citations
Sexually transmitted and blood‐borne infection risk reduction with methadone and buprenorphine/naloxone among people with prescription‐type opioid use disorder: Findings from a Canadian pragmatic randomized trial
HIV Medicine2024-03-201 citations
Pharmacogenetics of Biochemically Verified Abstinence in an Opioid Agonist Therapy Randomized Clinical Trial of Methadone and Buprenorphine/Naloxone
Clinical Pharmacology & Therapeutics2023-11-283 citations
Risk of relapse to non-opioid addictive substances among opioid dependent patients treated with an opioid receptor antagonist or a partial agonist: A randomized clinical trial.
2023-10-191 citations
The Association Between Self-Reported Anxiety and Retention in Opioid Agonist Therapy: Findings From a Canadian Pragmatic Trial
The Canadian Journal of Psychiatry2023-09-124 citations
Effects of Buprenorphine/Naloxone and Methadone on Depressive Symptoms in People with Prescription Opioid Use Disorder: A Pragmatic Randomised Controlled Trial
The Canadian Journal of Psychiatry2022-12-1410 citations
Design, methods, and recruitment outcomes of the Veterans' Pain Care Organizational Improvement Comparative Effectiveness (VOICE) study
Contemporary Clinical Trials2022-11-138 citations
Methamphetamine/amphetamine use over time among persons with opioid use disorders treated with buprenorphine/naloxone versus extended-release naltrexone.
2022-04-213 citations
Co-occurring Depression and Suicidal Ideation in Opioid Use Disorder
The Journal of Clinical Psychiatry2022-04-1511 citations
Association between methadone or buprenorphine use during medically supervised opioid withdrawal and extended-release injectable naltrexone induction failure.
2021-01-1611 citations
No increased pain among opioid‐dependent individuals treated with extended‐release naltrexone or buprenorphine‐naloxone: A 3‐month randomized study and 9‐month open‐treatment follow‐up study
American Journal on Addictions2019-01-3131 citations

6 more papers not shown