Bronchial challenge with allergen

PROCEDURE3 trials

Sponsors

Lithuanian University of Health Sciences

Conditions

Airway RemodellingAllergic AsthmaExtracellular Matrix AlterationSevere Eosinophilic Asthma

Unknown Phase

Eosinophil Induced Remodelling in Asthma

CompletedNCT02648074

Lithuanian University of Health SciencesAirway Remodelling, Allergic Asthma

Start: 2014-03-31End: 2017-01-31Updated: 2020-02-26

Role of Extracellular Matrix in the Development of Airway Remodeling in Asthma

Lithuanian University of Health SciencesAirway Remodelling, Allergic Asthma, Extracellular Matrix Alteration

Start: 2017-06-01End: 2020-12-08Target: 60Updated: 2020-09-07

Non-coding RNAs Analysis of Eosinophil Subtypes in Asthma

Lithuanian University of Health SciencesAllergic Asthma, Severe Eosinophilic Asthma

Start: 2020-10-01End: 2023-10-01Target: 80Updated: 2020-09-09

Related Papers

Serum Levels of Epithelial-Derived Cytokines as Interleukin-25 and Thymic Stromal Lymphopoietin after a Single Dose of Mepolizumab in Patients with Severe Non-Allergic Eosinophilic Asthma: A Short Report

Canadian Respiratory Journal2019-12-0117 citations

Expression of eosinophil β chain-signaling cytokines receptors, outer-membrane integrins, and type 2 inflammation biomarkers in severe non-allergic eosinophilic asthma.

2019-08-2221 citations

Suppression of Eosinophil Integrins Prevents Remodeling of Airway Smooth Muscle in Asthma

Frontiers in Physiology2017-01-0927 citations

Eosinophils enhance WNT-5a and TGF-β1 genes expression in airway smooth muscle cells and promote their proliferation by increased extracellular matrix proteins production in asthma.

2016-06-1336 citations