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Brivanib alaninate

DRUG5 trials

Sponsors

NCIC Clinical Trials Group, Bristol-Myers Squibb, Gynecologic Oncology Group, Abramson Cancer Center at Penn Medicine

Conditions

Advanced CancerCervical AdenocarcinomaCervical Adenosquamous CarcinomaCervical Squamous Cell Carcinoma, Not Otherwise SpecifiedColorectal CancerEndometrial AdenocarcinomaEndometrial Clear Cell AdenocarcinomaEndometrial Mixed Adenocarcinoma

Phase 1

Ascending Multiple-Dose Study of Brivanib Alaninate in Combination With Chemotherapeutic Agents in Subjects With Advanced Cancers
CompletedNCT00798252
Bristol-Myers SquibbAdvanced Cancer
Start: 2009-03-31End: 2015-05-31Updated: 2015-07-07

Phase 2

Brivanib Alaninate in Treating Patients With Recurrent or Persistent Endometrial Cancer
CompletedNCT00888173
Gynecologic Oncology GroupEndometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Mixed Adenocarcinoma +6
Start: 2009-07-06End: 2016-07-16Updated: 2017-12-06
Brivanib Metastatic Renal Cell Carcinoma
TerminatedNCT01253668
Abramson Cancer Center at Penn MedicineRenal Cell Carcinoma
Start: 2011-11-30End: 2013-09-30Updated: 2021-04-13
Brivanib Alaninate in Treating Patients With Persistent or Recurrent Cervical Cancer
CompletedNCT01267253
Gynecologic Oncology GroupCervical Adenocarcinoma, Cervical Adenosquamous Carcinoma, Cervical Squamous Cell Carcinoma, Not Otherwise Specified +2
Start: 2011-04-04End: 2014-02-28Updated: 2019-03-20

Phase 3

Cetuximab With or Without Brivanib in Treating Patients With K-Ras Wild Type Tumours and Metastatic Colorectal Cancer
CompletedNCT00640471
NCIC Clinical Trials GroupColorectal Cancer
Start: 2008-05-12End: 2013-01-10Updated: 2023-08-04

Related Papers

Machine Learning Models of Early Longitudinal Toxicity Trajectories Predict Cetuximab Concentration and Metastatic Colorectal Cancer Survival in the Canadian Cancer Trials Group/AGITG CO.17/20 Trials
JCO Clinical Cancer Informatics2025-04-01
A phases II evaluation of brivanib in the treatment of persistent or recurrent carcinoma of the cervix: An NRG Oncology/Gynecologic Oncology Group study.
Journal of Clinical Oncology2015-05-203 citations
Results of a feasibility study of I-124 girentuximab in metastatic clear cell renal cell carcinoma (m ccRCC).
Journal of Clinical Oncology2014-02-01