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Bridge Therapy

PROCEDURE4 trials

Sponsors

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Fred Hutchinson Cancer Center, University of Washington, City of Hope Medical Center

Conditions

Agitation, EmergenceEmergence DeliriumMigraine, HemicraniaProstate CarcinomaProstate Small Cell Neuroendocrine CarcinomaRecurrent B Acute Lymphoblastic LeukemiaRecurrent B Lymphoblastic LymphomaRefractory B Acute Lymphoblastic Leukemia

Phase 1

Autologous T Cells Lentivirally Transduced to Express L1CAM-Specific Chimeric Antigen Receptors in Treating Patients With Locally Advanced and Unresectable or Metastatic Small Cell Neuroendocrine Prostate Cancer
WithdrawnNCT06094842
Fred Hutchinson Cancer CenterProstate Carcinoma, Prostate Small Cell Neuroendocrine Carcinoma, Stage III Prostate Cancer AJCC v8 +1
Start: 2025-04-15End: 2028-03-15Updated: 2025-04-01
Genetically Engineered Cells (BAFFR-CAR T Cells) for the Treatment of Relapsed or Refractory B-cell Acute Lymphoblastic Leukemia and B-cell Lymphoblastic Lymphoma
Not yet recruitingNCT07758673
City of Hope Medical CenterRecurrent B Acute Lymphoblastic Leukemia, Recurrent B Lymphoblastic Lymphoma, Refractory B Acute Lymphoblastic Leukemia +1
Start: 2027-04-17End: 2028-07-26Target: 16Updated: 2026-08-11

Phase 4

Home Detox in Medication Overuse Headache (MOH) During Covid-19 Emergency
CompletedNCT04410536
Fondazione I.R.C.C.S. Istituto Neurologico Carlo BestaMigraine, Hemicrania
Start: 2020-06-15End: 2022-07-31Updated: 2025-01-23

Unknown Phase

Mitigation of Emergence Agitation Through Implementation of Masimo Bridge Therapy
WithdrawnNCT06387953
University of WashingtonAgitation, Emergence, Emergence Delirium
Start: 2024-08-27End: 2024-08-27Updated: 2024-10-16