Brain Surgery

PROCEDURE7 trials

Sponsors

University of Pennsylvania, AHS Cancer Control Alberta, Mayo Clinic, Institut Català d'Oncologia, NRG Oncology

Conditions

Brain MetastasesBrain NeoplasmBrain NeoplasmsChronic Ischemic StrokeGlioblastomaGliomaMalignant Brain NeoplasmMeningioma

Phase 1

Zr-89 Crefmirlimab Berdoxam and Immuno-Positron Emission Tomography for the Imaging of Patients With Resectable Brain Tumors

RecruitingNCT06650163

Jonsson Comprehensive Cancer CenterGlioma, Malignant Brain Neoplasm, Meningioma +1

Start: 2024-12-05End: 2028-01-31Target: 20Updated: 2026-02-05

A Study of ASP2246 for People Who Have Movement Problems Caused by Brain Injury After a Stroke

Not yet recruitingNCT07318714

Astellas Pharma IncChronic Ischemic Stroke

Start: 2026-04-07End: 2030-02-28Target: 84Updated: 2026-04-03

Phase 2

Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma

Active, not recruitingNCT04225039

University of PennsylvaniaGlioblastoma

Start: 2020-06-23End: 2029-04-30Updated: 2025-08-15

IORT After Surgical Resection of Brain Metastases

Institut Català d'OncologiaBrain Neoplasms

Start: 2020-06-17End: 2024-12-31Target: 40Updated: 2022-08-04

Phase 3

Pre- Versus Post-operative SRS for Resectable Brain Metastases

TerminatedNCT04474925

AHS Cancer Control AlbertaBrain Metastases

Start: 2021-09-27End: 2025-04-07Updated: 2025-07-18

Comparing the Addition of Radiation Either Before or After Surgery for Patients With Brain Metastases

Active, not recruitingNCT05438212

NRG OncologyMetastatic Malignant Neoplasm in the Brain

Start: 2022-10-24End: 2027-03-16Updated: 2026-04-03

Unknown Phase

Surgical Resection of Latent Brain Tumors Prior to Recurrence

SuspendedNCT04810871

Mayo ClinicBrain Neoplasm

Start: 2021-05-06End: 2028-03-01Target: 40Updated: 2026-01-30

Related Papers

Pre-operative vs. post-operative stereotactic radiosurgery for operative metastatic brain tumors: study protocol for a phase III clinical trial.

2024-03-124 citations

Single-Fraction Versus Fractionated Preoperative Radiosurgery for Resected Brain Metastases: A PROPS-BM International Multicenter Cohort Study.

2023-09-1613 citations

Risk Factors for Progression and Toxic Effects After Preoperative Stereotactic Radiosurgery for Patients With Resected Brain Metastases

JAMA Oncology2023-06-0825 citations

PD1 inhibition and GITR agonism in combination with fractionated stereotactic radiotherapy for the treatment of recurrent glioblastoma: A phase 2, multi-arm study.

Journal of Clinical Oncology2023-06-017 citations

A phase III, multicenter, randomized controlled trial of preoperative versus postoperative stereotactic radiosurgery for patients with surgically resectable brain metastases

BMC Cancer2022-12-3023 citations