BQ-123

DRUG8 trials

Conditions

Aorto-coronary Bypass GraftingCardiovascular DiseasesCardiovascular Risk FactorChronic Obstructive Pulmonary DiseaseCoronary Artery DiseaseHealthyHeart FailureHypertension

Early Phase 1

Contribution of Endothelin-1 to Exercise Intolerance in Heart Failure

CompletedNCT02124824

VA Office of Research and DevelopmentHeart Failure

Start: 2014-09-01End: 2019-03-31Updated: 2021-12-20

Phase 1

: Vascular Function in Health and Disease

RecruitingNCT02966665

Russell RichardsonChronic Obstructive Pulmonary Disease, Heart Failure, Hypertension +1

Start: 2008-09-30End: 2026-08-31Target: 420Updated: 2025-09-26

The Effect of Endothelin and L-Arginine on Racial Differences in Vasoconstriction

CompletedNCT03679780

The University of Texas at ArlingtonCardiovascular Diseases, Cardiovascular Risk Factor, Vasoconstriction

Start: 2018-10-01End: 2023-07-26Updated: 2024-06-11

Phase 2

Endothelin Receptor Blockade in Acute ST-elevation Myocardial Infarction

CompletedNCT00502528

Medical University of ViennaST-Elevation Myocardial Infarction

Start: 2007-05-31End: 2012-08-31Updated: 2013-04-30

Role of Endothelin in Microvascular Dysfunction Following PCI for NSTEMI

CompletedNCT00586820

Mayo ClinicMyocardial Reperfusion Injury

Start: 2005-05-31End: 2012-01-31Updated: 2014-07-04

The Role of Endothelin in Pulmonary Hypertension

CompletedNCT00759408

Brigham and Women's HospitalPulmonary Hypertension

Start: 1999-02-28End: 2011-06-30Updated: 2018-11-27

Short-term Endothelin A Receptor Blockade in Patients With On-pump CABG

NCT01658410

Medical University of ViennaAorto-coronary Bypass Grafting, Coronary Artery Disease

Start: 2012-07-31End: 2016-12-31Target: 120Updated: 2012-08-07

Unknown Phase

Role of Endothelin-1 in Optic Nerve Head Blood Flow Regulation During Isometric Exercise in Healthy Humans

CompletedNCT00915070

Medical University of ViennaHealthy

Start: 2010-10-31End: 2011-12-31Updated: 2012-08-10

Related Papers

Respiratory Pathophysiology Through the Lens of Mitochondria

Clinical bioenergetics2025-06-05

Role of endothelin in microvascular dysfunction following percutaneous coronary intervention for non-ST elevation acute coronary syndromes: a single-centre randomised controlled trial

Open Heart2016-08-0116 citations