Bosulif 100 mg film-coated tablets

DRUG3 trials

Sponsors

Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC), Ascentage Pharma Group Inc., Centre Hospitalier Universitaire De Poitiers

Conditions

Chronic Myeloid LeukemiaChronic Phase Chronic Myeloid Leukemia

Phase 1

A Phase I/II study of Bosutinib in pediatric patients with newly diagnosed chronic phase or resistant/intolerant Ph+ Chronic Myeloid Leukemia, study ITCC-054/COG AAML1921

Active, not recruitingCTIS2023-504311-32-00

Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)Chronic Myeloid Leukemia

Start: 2016-09-02Target: 30Updated: 2025-12-09

Phase 3

AITIK-Discontinuation of TyrosIne Kinase Inhibitors (ITK) in Chronic Myeloid Leukemia (LMC) and Impact on the Immune System: a Randomized Comparative Study of Two Therapeutic Strategies

Active, not recruitingCTIS2024-515479-36-00

Centre Hospitalier Universitaire De PoitiersChronic Myeloid Leukemia

Start: 2023-07-05Target: 170Updated: 2025-06-05

A Global Multicenter, Open Label, Randomized, Phase 3 Registrational Study of Olverembatinib (HQP1351) in Patients with Chronic Phase Chronic Myeloid Leukemia (POLARIS-2)

RecruitingCTIS2024-511495-32-00

Ascentage Pharma Group Inc.Chronic Phase Chronic Myeloid Leukemia

Start: 2025-04-16Target: 68Updated: 2025-08-25