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Bortezomib Hikma 3
DRUG
3 trials
Sponsors
Alexion Pharmaceuticals Inc.
, Glaxosmithkline Research & Development Limited
, AstraZeneca AB
Conditions
HYPOPHOSPHATASIA
Relapsed or Refractory Multiple Myeloma
newly diagnosed amyloid light chain amyloidosis
Phase 2
A Phase 2, open-label, randomized, dose optimization study evaluating the efficacy and safety of belantamab mafodotin administered in combination with cyclophosphamide, bortezomib, and dexamethasone in adult participants with newly diagnosed amyloid light chain amyloidosis (ALANIS)
Not yet recruiting
CTIS2025-522803-60-00
Glaxosmithkline Research & Development Limited
newly diagnosed amyloid light chain amyloidosis
Target: 17
Updated: 2026-07-22
Phase 3
A Phase III Open-label, Randomised, Multicentre Study Comparing AZD0120, a Dual-Targeting Autologous Chimeric Antigen Receptor T-cell (CAR-T) Therapy Directed Against BCMA and CD19, versus Standard Regimens in Participants with Relapsed Refractory Multiple Myeloma (DURGA-4)
Not yet recruiting
CTIS2025-523285-25-00
AstraZeneca AB
Relapsed or Refractory Multiple Myeloma
Target: 38
Updated: 2026-04-30
Phase 4
An Interventional, Prospective Open-Label Study of Immunosuppressive Therapies to Mitigate Immune-Mediated Loss of Therapeutic Response to Asfotase Alfa (STRENSIQ®) for Hypophosphatasia (RESTORE)
Completed
CTIS2022-502793-17-00
Alexion Pharmaceuticals Inc.
HYPOPHOSPHATASIA
End: 2025-08-08
Target: 1
Updated: 2024-09-19