bOPV

BIOLOGICAL6 trials

Sponsors

University of Chile, Aga Khan University, University of Virginia, PT Bio Farma, Centers for Disease Control and Prevention

Conditions

HealthyOral Polio VaccinePolioPoliomyelitisVaccine Virus Shedding

Phase 3

Assessment of Community Transmission of Sabin Type 2 Virus in Bangladesh

University of VirginiaVaccine Virus Shedding

Start: 2015-04-30End: 2017-06-30Target: 810Updated: 2016-10-26

Phase 4

Immunogenicity of 1 or 2 Doses of bOPV in Chilean Infants Primed With IPV Vaccine

University of ChilePolio

Start: 2013-04-30End: 2014-06-30Target: 570Updated: 2014-05-20

Polio End-game Strategies - Poliovirus Type 2 Challenge Study

CompletedNCT02189811

Aga Khan UniversityPoliomyelitis

Start: 2014-09-30End: 2016-05-31Updated: 2016-05-03

Immunogenicity and Safety Profile of Primary Dose of bOPV Bio Farma Given Simultaneously With Pentabio And IPV

CompletedNCT03310073

PT Bio FarmaHealthy

Start: 2016-07-31End: 2017-03-31Updated: 2017-11-08

Monovalent Oral Poliovirus Vaccine Type 1 Intestinal and Humoral Immunity Study

CompletedNCT03722004

Centers for Disease Control and PreventionPoliomyelitis

Start: 2018-12-18End: 2019-12-19Updated: 2021-02-21

Unknown Phase

Use of mOPV1 in Routine Immunization in Pakistan.

Aga Khan UniversityOral Polio Vaccine

Start: 2020-08-31End: 2021-12-31Target: 560Updated: 2020-08-07

Related Papers

Poliovirus type 1 systemic humoral and intestinal mucosal immunity induced by monovalent oral poliovirus vaccine, fractional inactivated poliovirus vaccine, and bivalent oral poliovirus vaccine: A randomized controlled trial.

2023-08-294 citations

Multiscale model for forecasting Sabin 2 vaccine virus household and community transmission

PLoS Computational Biology2021-12-217 citations

Intestinal Immunity to Poliovirus Following Sequential Trivalent Inactivated Polio Vaccine/Bivalent Oral Polio Vaccine and Trivalent Inactivated Polio Vaccine-only Immunization Schedules: Analysis of an Open-label, Randomized, Controlled Trial in Chilean Infants.

2018-10-0118 citations

Evaluation of vaccine derived poliovirus type 2 outbreak response options: A randomized controlled trial, Karachi, Pakistan

Vaccine2018-02-2313 citations

Community transmission of type 2 poliovirus after cessation of trivalent oral polio vaccine in Bangladesh: an open-label cluster-randomised trial and modelling study.

2017-07-0723 citations

Inactivated poliovirus vaccine given alone or in a sequential schedule with bivalent oral poliovirus vaccine in Chilean infants: a randomised, controlled, open-label, phase 4, non-inferiority study.

2015-08-2659 citations