Bone Marrow Derived MSCs

BIOLOGICAL2 trials

Sponsors

Emory University, Next Generation Regenerative Medicine LLC

Conditions

OsteoarthritisOsteoarthritis, Knee

Phase 1

Mesenchymal Stem Cell Therapy for Knee Osteoarthritis

Next Generation Regenerative Medicine LLCOsteoarthritis, Knee

Start: 2022-08-31End: 2024-12-31Target: 120Updated: 2022-03-21

Phase 3

Multicenter Trial of Stem Cell Therapy for Osteoarthritis (MILES)

CompletedNCT03818737

Emory UniversityOsteoarthritis

Start: 2019-03-28End: 2022-05-31Updated: 2023-07-27

Related Papers

SPOT: An Early Detection Tool for Predicting Pain Trajectories Following Intra‐Articular Injections

Journal of Orthopaedic Research®2026-08-31

Autologous Cell Injections for Knee Osteoarthritis Display Greater Responsiveness Than Allogenic Cellular Products and Corticosteroids in a Sex-Dependent Manner

The American Journal of Sports Medicine2025-09-27

On-chip 3D potency assay for prediction of clinical outcomes for cell therapy candidates for osteoarthritis

Nature Communications2025-05-273 citations

Single-cell transcriptome and crosstalk analysis reveals immune alterations and key pathways in the bone marrow of knee OA patients.

2024-08-267 citations

Cell-based versus corticosteroid injections for knee pain in osteoarthritis: a randomized phase 3 trial.

2023-11-0264 citations