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BNT327 20 mg ml

DRUG7 trials

Sponsors

Bristol-Myers Squibb Services Unlimited Company

Conditions

Advanced and/or Metastatic Solid Tumors with Homozygous MTAP DeletionAdvanced or unresectable Hepatocellular Carcinoma (HCC)Gastroesophageal JunctionLocally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)Non-Small Cell Lung CancerPreviously Untreated Advanced or Metastatic GastricUnresectable Stage III non-small cell lung cancer without progressionUnresectable or Metastatic Colorectal Cancer

Phase 1

Phase 2

ROSETTA Gastric-204: A Blinded, Randomized, Phase 2/3 Study of Pumitamig in Combination with Chemotherapy Versus Nivolumab in Combination with Chemotherapy in Participants with Previously Untreated Advanced or Metastatic Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Not yet recruitingCTIS2025-523263-37-00
Bristol-Myers Squibb Services Unlimited CompanyGastroesophageal Junction, or Esophageal Adenocarcinoma, Previously Untreated Advanced or Metastatic Gastric
Target: 40Updated: 2026-03-10
ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination with Chemotherapy Versus Bevacizumab in Combination with Chemotherapy in Participants with Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Not yet recruitingCTIS2025-523224-45-00
Bristol-Myers Squibb Services Unlimited CompanyUnresectable or Metastatic Colorectal Cancer, Untreated
Target: 33Updated: 2026-03-11
A Phase 2 Open-Label, Multi-Center Study of BMS-986504 as Monotherapy and in Combination with Other Agents in Participants with Advanced and/or Metastatic Solid Tumors with Homozygous MTAP Deletion
Not yet recruitingCTIS2025-524285-18-00
Bristol-Myers Squibb Services Unlimited CompanyAdvanced and/or Metastatic Solid Tumors with Homozygous MTAP Deletion
Target: 67Updated: 2026-07-08
A Phase 2, Randomized, Open-label, Study Assessing the Safety, Tolerability and Efficacy of Imzokitug in Combination with Pumitamig and Platinum-Doublet Chemotherapy (PDCT) versus Pumitamig and PDCT as First-line Treatment for Participants with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Not yet recruitingCTIS2026-525170-19-00
Bristol-Myers Squibb Services Unlimited CompanyLocally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Target: 17Updated: 2026-09-07

Phase 3