BNT327 20 mg ml
Sponsors
Bristol-Myers Squibb Services Unlimited Company
Conditions
Advanced and/or Metastatic Solid Tumors with Homozygous MTAP DeletionAdvanced or unresectable Hepatocellular Carcinoma (HCC)Gastroesophageal
JunctionLocally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)Non-Small Cell Lung CancerPreviously Untreated Advanced or Metastatic GastricUnresectable Stage III non-small cell lung cancer without progressionUnresectable or Metastatic Colorectal Cancer
Phase 1
Phase 2
ROSETTA Gastric-204: A Blinded, Randomized, Phase 2/3 Study of Pumitamig in
Combination with Chemotherapy Versus Nivolumab in Combination with
Chemotherapy in Participants with Previously Untreated Advanced or Metastatic
Gastric, Gastroesophageal Junction, or Esophageal Adenocarcinoma
Not yet recruitingCTIS2025-523263-37-00
Target: 40Updated: 2026-03-10
ROSETTA CRC-203: A Blinded, Randomized Phase 2/3 Study of Pumitamig in Combination with Chemotherapy Versus Bevacizumab in Combination with Chemotherapy in Participants with Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Not yet recruitingCTIS2025-523224-45-00
Target: 33Updated: 2026-03-11
A Phase 2 Open-Label, Multi-Center Study of BMS-986504 as Monotherapy and in Combination with Other Agents in Participants with Advanced and/or Metastatic Solid Tumors with Homozygous MTAP Deletion
Not yet recruitingCTIS2025-524285-18-00
Target: 67Updated: 2026-07-08
A Phase 2, Randomized, Open-label, Study Assessing the Safety, Tolerability and Efficacy of Imzokitug in Combination with Pumitamig and Platinum-Doublet Chemotherapy (PDCT) versus Pumitamig and PDCT as First-line Treatment for Participants with Locally Advanced or Metastatic Non-Small Cell Lung Cancer (NSCLC)
Not yet recruitingCTIS2026-525170-19-00
Target: 17Updated: 2026-09-07
Phase 3
ROSETTA Lung-202: A Randomized, Double-Blind, Phase 3 Study of Pumitamig Monotherapy Compared to Pembrolizumab as First-line Treatment in Participants with Locally Advanced or Metastatic Non-Small Cell Lung Cancer with PD-L1 ≥ 50%
Not yet recruitingCTIS2025-523586-18-00
Target: 31Updated: 2026-05-18
ROSETTA Lung-201: A Randomized, Multicenter, Open-label Phase 3 study of Pumitamig Monotherapy Compared to Durvalumab in Participants with Unresectable Stage III NSCLC Without Progression After Platinum-based Concurrent Chemoradiation Therapy
Not yet recruitingCTIS2025-523576-23-00
Target: 62Updated: 2026-05-22