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BMS-986231

DRUG5 trials

Sponsors

Bristol-Myers Squibb

Conditions

Cardiac FailureCongestive Heart FailureHeart DecompensationHeart Decompensation, AcuteHepatic FailureKidney FailureLiver DysfunctionLiver Insufficiency

Phase 1

Study With Healthy Japanese and Non-Asian Participants With BMS-986231
CompletedNCT02932969
Bristol-Myers SquibbHeart Decompensation, Acute
Start: 2016-10-04End: 2017-05-26Updated: 2017-05-31
Pharmacokinetics and Metabolism of [14C] BMS-986231 in Healthy Male Participants
CompletedNCT03210909
Bristol-Myers SquibbHeart Decompensation, Acute
Start: 2017-06-22End: 2017-07-20Updated: 2017-08-01
A Study of Experimental Medication BMS-986231 in Patients With Different Levels of Kidney Function
CompletedNCT03332186
Bristol-Myers SquibbCardiac Failure, Congestive Heart Failure, Kidney Failure +2
Start: 2018-03-15End: 2018-10-22Updated: 2019-09-11
An Investigational Study of Experimental Medication BMS-986231 Given in Participants With Different Levels of Liver Function
CompletedNCT03515980
Bristol-Myers SquibbCardiac Failure, Congestive Heart Failure, Heart Decompensation +4
Start: 2018-05-25End: 2019-08-29Updated: 2020-08-27

Phase 2

An Investigational Study of Continuous 8-Hour Intravenous Administrations of BMS-986231 in Participants With Heart Failure and Reduced Heart Function Given a Standard Dose of Loop Diuretic
CompletedNCT03730961
Bristol-Myers SquibbCardiac Failure, Congestive Heart Failure, Heart Decompensation +1
Start: 2019-01-17End: 2020-01-09Updated: 2021-02-26