Blood Brain Barrier (BBB) Disruption

DEVICE2 trials

Sponsors

InSightec

Conditions

Alzheimer Disease

Unknown Phase

ExAblate Blood-Brain Barrier (BBB) Disruption for the Treatment of Alzheimer's Disease

RecruitingNCT03671889

InSightecAlzheimer Disease

Start: 2018-09-28End: 2030-01-31Target: 50Updated: 2026-01-09

ExAblate Blood-Brain Barrier Opening for Treatment of Alzheimer's Disease

CompletedNCT03739905

InSightecAlzheimer Disease

Start: 2018-12-06End: 2025-04-09Updated: 2026-01-21

Related Papers

Ultrasound-mediated blood–brain barrier opening uncovers an intracerebral perivenous fluid network in persons with Alzheimer’s disease

Fluids and Barriers of the CNS2023-06-1655 citations

Blood–brain barrier opening of the default mode network in Alzheimer’s disease with magnetic resonance-guided focused ultrasound

Brain2023-01-2561 citations

Focused ultrasound mitigates pathology and improves spatial memory in Alzheimer's mice and patients

Theranostics2023-01-0138 citations

MR-guided focused ultrasound liquid biopsy enriches circulating biomarkers in patients with brain tumors

Neuro-Oncology2021-03-09144 citations

Blood-Brain Barrier Opening with MRI-guided Focused Ultrasound Elicits Meningeal Venous Permeability in Humans with Early Alzheimer Disease

Radiology2021-01-05117 citations