Biotin-labeled red blood cells

BIOLOGICAL2 trials

Sponsors

Gladwin, Mark, MD, National Heart, Lung, and Blood Institute (NHLBI)

Conditions

Healthy VolunteersHemoglobinopathySickle Cell DiseaseThalassemia

Early Phase 1

Determination of Red Cell Survival in Sickle Cell Disease and Other Hemoglobinopathies Using Biotin Labeling

RecruitingNCT06313398

National Heart, Lung, and Blood Institute (NHLBI)Hemoglobinopathy, Sickle Cell Disease, Thalassemia

Start: 2024-05-17End: 2029-06-15Target: 100Updated: 2026-08-31

Phase 2

Transfusion of Biotin-Labeled Red Blood Cells

TerminatedNCT03364686

Gladwin, Mark, MDHealthy Volunteers

Start: 2019-09-16End: 2021-06-29Updated: 2022-04-21