BIA 5-453

DRUG5 trials

Sponsors

Bial - Portela C S.A.

Conditions

Chronic Heart FailureCongestive Heart FailureHypertension

Phase 1

Tolerability, Pharmacokinetics and Pharmacodynamics of Six Multiple Rising Dose Regimens of BIA 5-453

CompletedNCT02840565

Bial - Portela C S.A.Chronic Heart Failure, Hypertension

Start: 2007-09-30End: 2008-07-31Updated: 2016-07-21

Tolerability, Pharmacokinetics and Dopamine ß-hydroxylase (DßH) Inhibition Profile of BIA 5-453

CompletedNCT02845037

Bial - Portela C S.A.Chronic Heart Failure, Hypertension

Start: 2007-05-31End: 2007-09-30Updated: 2016-07-26

Bioavailability Study of BIA 5-453

CompletedNCT03090568

Bial - Portela C S.A.Congestive Heart Failure, Hypertension

Start: 2008-07-15End: 2008-08-14Updated: 2017-03-27

Pharmacokinetics of BIA 5-453 and Its Metabolites

CompletedNCT03090724

Bial - Portela C S.A.Chronic Heart Failure, Hypertension

Start: 2008-06-13End: 2008-08-12Updated: 2017-03-27

Tolerability, Pharmacokinetics and Pharmacodynamics of Multiple Rising Dose Regimens of BIA 5-453

CompletedNCT03099226

Bial - Portela C S.A.Hypertension

Start: 2008-07-15End: 2009-04-03Updated: 2017-04-04