BI 1358894
Sponsors
Boehringer Ingelheim
Conditions
Borderline Personality DisorderDepressive Disorder, MajorHealthyPost-Traumatic Stress Disorder
Phase 1
This Study in Healthy Men Tests How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Looks at How Food Influences the Amount of BI 1358894 in the Blood
CompletedNCT03210272
Start: 2017-07-18End: 2019-02-18Updated: 2025-03-25
This Study in Healthy Men Tests How Different Doses of BI 1358894 Are Taken up in the Body and How Well They Are Tolerated. The Study Also Tests How BI 1358894 Affects the Way the Body Breaks Down Midazolam
CompletedNCT03754959
Start: 2018-12-18End: 2019-07-22Updated: 2025-04-03
A Study in Healthy Men to Test How Itraconazole Influences the Amount of BI 1358894 in the Blood
CompletedNCT03843151
Start: 2019-03-19End: 2019-06-03Updated: 2025-02-21
A Study in People With Depression to Test the Effects of BI 1358894 on Parts of the Brain That Are Involved in Emotions
CompletedNCT03854578
Start: 2019-03-12End: 2019-09-23Updated: 2025-02-25
A Study in Healthy Men to Test Whether BI 1358894 Reduces Druginduced Panic Symptoms
CompletedNCT03904576
Start: 2019-04-18End: 2019-08-29Updated: 2025-03-19
A Study in Healthy Men to Test the Influence of BI 1358894 on the Amount of the Medicines Rosuvastatin and Dabigatran in the Blood
CompletedNCT04099732
Start: 2019-10-07End: 2019-12-10Updated: 2025-02-27
A Study in Healthy Men to Test How BI 1358894 is Taken up in the Body and How Food Influences the Amount of BI 1358894 in the Blood
CompletedNCT04426851
Start: 2020-07-13End: 2020-10-12Updated: 2025-03-30
A Study in Healthy Men to Test How BI 1358894 is Taken up and Handled by the Body
CompletedNCT04567316
Start: 2020-10-19End: 2021-01-10Updated: 2025-02-27
A Study in Healthy Men and Women to Test Whether BI 1358894 Influences the Amount of Bupropion in the Blood
CompletedNCT04899674
Start: 2021-06-30End: 2021-09-02Updated: 2025-02-24
A Study in Healthy Women to Test Whether BI 1358894 Influences the Amount of a Contraceptive in the Blood
TerminatedNCT05934942
Start: 2023-09-08End: 2024-02-08Updated: 2025-02-24
Phase 2
A Home-based Study Using Mobile Technology to Test Whether BI 1358894 is Effective in People With Depression
TerminatedNCT04423757
Start: 2020-06-22End: 2022-05-08Updated: 2023-06-13
A Study to Test the Effect of Different Doses of BI 1358894 and Quetiapine in People With Depression
CompletedNCT04521478
Start: 2020-11-20End: 2024-02-02Updated: 2025-03-06
A Study to Test Different Doses of BI 1358894 and Find Out Whether They Reduce Symptoms in People With Borderline Personality Disorder
CompletedNCT04566601
Start: 2020-11-13End: 2023-01-25Updated: 2024-01-30
A Study to Test Whether Taking BI 1358894 for 8 Weeks Helps Adults With Post-traumatic Stress Disorder
CompletedNCT05103657
Start: 2021-12-07End: 2023-11-20Updated: 2024-11-07