Berberine Hydrochloride

DRUG8 trials

Conditions

Blood PressureColorectal AdenomaColorectal AdenomasColorectal Cancer Control and PreventionColorectal CancersColorectal PolypsEndothelial DysfunctionGastric Intestinal Metaplasia

Phase 2

Effects of Berberine Hydrochloride and Bifidobacterium in Prediabetes Prevention and Treatment

WithdrawnNCT02082756

Xijing HospitalPrediabetes

Start: 2015-11-30End: 2018-04-30Updated: 2018-11-14

Effects of Berberine Hydrochloride and Bifidobacterium in Diabetes Mellitus Prevention and Treatment

WithdrawnNCT02084004

Xijing HospitalType 2 Diabetes Mellitus

Start: 2015-11-30End: 2018-04-30Updated: 2018-11-14

Study of Berberine Hydrochloride in Prevention of Colorectal Adenomas Recurrence

CompletedNCT02226185

Shanghai Jiao Tong University School of MedicineColorectal Adenoma

Start: 2014-11-30End: 2018-12-29Updated: 2019-03-26

A Research of Berberine Hydrochloride to Prevent Colorectal Adenomas in Patients With Previous Colorectal Cancer

CompletedNCT03281096

Xijing Hospital of Digestive DiseasesColorectal Adenomas

Start: 2017-08-29End: 2021-03-01Updated: 2022-07-27

Phase 4

Effect of Berberine Hydrochloride on Blood Pressure and Vascular Endothelial Function in Patients With Hypertension

NCT04790942

Jun TaoBlood Pressure, Endothelial Dysfunction, Hypertension

Start: 2020-10-22End: 2022-05-22Target: 30Updated: 2021-03-10

Efficacy and Safety of Berberine for Gastric Intestinal Metaplasia

Not yet recruitingNCT07129460

Xijing Hospital of Digestive DiseasesGastric Intestinal Metaplasia

Start: 2025-10-01End: 2027-05-01Target: 204Updated: 2025-09-04

Unknown Phase

6-year Follow-up Data After the Berberine Intervention Trial

RecruitingNCT06629051

Shanghai Jiao Tong University School of MedicineColorectal Adenoma, Colorectal Cancer Control and Prevention, Colorectal Polyps

Start: 2024-10-04End: 2024-12-31Target: 891Updated: 2024-10-08

Effects of Berberine on the Human Gut Microbiome

Not yet recruitingNCT07519681

Jing-yuan Fang, MD, Ph. DColorectal Adenomas, Colorectal Cancers

Start: 2026-05-15End: 2026-10-15Target: 20Updated: 2026-05-11

Related Papers

Berberine for preventing colorectal adenoma recurrence and neoplasm occurrence: 6-Year follow-up of a randomized clinical trial.

2025-08-11

Berberine might block colorectal carcinogenesis by inhibiting the regulation of B-cell function by Veillonella parvula

Chinese Medical Journal2023-08-0922 citations

Berberine versus placebo for the prevention of recurrence of colorectal adenoma: a multicentre, double-blinded, randomised controlled study.

2020-01-08135 citations