Benzbromarone

DRUG8 trials

Conditions

Abnormal Renal FunctionChronic Kidney DiseaseGoutGout and Asymptomatic HyperuricemiaHyperuricemiaHyperuricemia With or Without GoutIdiopathic Pulmonary Arterial Hypertension

Phase 1

A PD/Safety Study of RDEA3170 in Combination With Febuxostat for Treating Gout or Asymptomatic Hyperuricemia Patients

CompletedNCT02317861

AstraZenecaGout and Asymptomatic Hyperuricemia

Start: 2014-12-31End: 2015-06-30Updated: 2015-06-12

Phase 2

Acute Effects of Benzbromaron on the Pulmonary Circulation

CompletedNCT02790450

Medical University of GrazIdiopathic Pulmonary Arterial Hypertension

Start: 2015-10-31End: 2016-08-31Updated: 2016-12-23

Dose-finding and Safety Study of SHR4640 in Subjects With Hyperuricemia

CompletedNCT03185793

Jiangsu HengRui Medicine Co., Ltd.Hyperuricemia

Start: 2017-07-20End: 2018-07-20Updated: 2019-08-07

Evaluate the Efficacy and Safety of D-0120 in Primary Hyperuricemia Patients

CompletedNCT05504083

InventisBio Co., LtdHyperuricemia

Start: 2022-09-28End: 2024-05-18Updated: 2024-10-15

Phase 3

Benzbromarone-Controlled, Double-Blind, Comparative Study of FYU-981 in Hyperuricemia With or Without Gout

CompletedNCT03100318

Fuji Yakuhin Co., Ltd.Hyperuricemia With or Without Gout

Start: 2017-04-01End: 2018-08-31Updated: 2018-09-26

Phase 4

GOut TrEatment STrategy (GO TEST) FINALE study, a multicentre pragmatic randomized superiority trial of continuation versus cessation of urate lowering therapies in gout in remission.

CompletedCTIS2024-511111-13-01

Sint MaartenskliniekGout

Start: 2024-07-09End: 2025-06-16Target: 310Updated: 2024-07-09

Unknown Phase

Compare the Renal Protective Effects of Febuxostat and Benzbromarone

CompletedNCT02338323

Shanghai 10th People's HospitalAbnormal Renal Function, Chronic Kidney Disease, Hyperuricemia

Start: 2015-01-31End: 2018-12-31Updated: 2019-07-24

Compare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients

NCT02944214

Shanghai 10th People's HospitalAbnormal Renal Function, Chronic Kidney Disease, Hyperuricemia

Start: 2016-10-31End: 2019-12-31Target: 800Updated: 2016-10-25

Clinical and Experimental Hypertension2021-08-2324 citations

Efficacy and safety of a selective URAT1 inhibitor SHR4640 in Chinese subjects with hyperuricaemia: a randomized controlled phase II study

Lara D. Veeken2021-03-0433 citations

Higher Febuxostat Exposure Observed in Asian Compared with Caucasian Subjects Independent of Bodyweight.

2020-09-195 citations

Dotinurad versus benzbromarone in Japanese hyperuricemic patient with or without gout: a randomized, double-blind, parallel-group, phase 3 study.

2020-01-2436 citations

Verinurad combined with febuxostat in Japanese adults with gout or asymptomatic hyperuricaemia: a phase 2a, open-label study

Lara D. Veeken2018-04-1232 citations