Bempedoic acid 180 mg tablet

DRUG2 trials

Sponsors

Esperion Therapeutics, Inc., Daiichi Sankyo

Conditions

Cardiovascular DiseasesPrimary Hypercholesterolemia or Mixed HyperlipidemiaStatin Adverse Reaction

Phase 3

Evaluation of Major Cardiovascular Events in Participants With, or at High Risk for, Cardiovascular Disease Who Are Statin Intolerant Treated With Bempedoic Acid (ETC-1002) or Placebo

CompletedNCT02993406

Esperion Therapeutics, Inc.Cardiovascular Diseases, Statin Adverse Reaction

Start: 2016-12-22End: 2022-11-07Updated: 2024-01-03

Phase 4

A Study to Investigate the Effectiveness and Safety of Bempedoic Acid in Patients With Primary Hypercholesterolemia or Mixed Dyslipidemia in Taiwan

CompletedNCT06925100

Daiichi SankyoPrimary Hypercholesterolemia or Mixed Hyperlipidemia

Start: 2025-04-01End: 2025-10-15Updated: 2025-12-08

Related Papers

Effectiveness and Safety of Bempedoic Acid Across Clinically Relevant Subgroups: Insights from the CLEAR Taiwan Study

medRxiv2026-06-18

Bempedoic Acid and Venous Thromboembolism Risk Among Statin-Intolerant Patients: A Post Hoc Analysis of the CLEAR Outcomes Randomized Clinical Trial.

2026-05-27

Effectiveness and Safety of Bempedoic Acid in Taiwanese Patients With Hypercholesterolemia: A Pragmatic Phase 4 Study (CLEAR Taiwan Study)

Journal of the American Heart Association2026-05-14

Sex Differences in Statin Intolerance: Insights From the CLEAR Outcomes Trial

Clinical Cardiology2026-04-01

Cost-Effectiveness of Bempedoic Acid in High Cardiovascular Risk Patients with Statin Intolerance: An Analysis of the CLEAR Outcomes Trial.

2025-08-201 citations

Bempedoic Acid for Prevention of Cardiovascular Events in People With Obesity: A CLEAR Outcomes Subset Analysis

Journal of the American Heart Association2025-02-082 citations

Characteristics and outcomes of patients with and without statin-associated muscle symptoms treated with bempedoic acid in the CLEAR Outcomes trial.

2024-12-254 citations

Comparative Cardiovascular Benefits of Bempedoic Acid and Statin Drugs

Journal of the American College of Cardiology2024-07-0122 citations

Efficacy and safety of bempedoic acid among patients with and without diabetes: prespecified analysis of the CLEAR Outcomes randomised trial.

2023-12-0453 citations

Inflammation and Cholesterol as Predictors of Cardiovascular Events Among 13 970 Contemporary High-Risk Patients With Statin Intolerance

Circulation2023-11-06102 citations

Bempedoic Acid for Primary Prevention of Cardiovascular Events in Statin-Intolerant Patients

JAMA2023-06-24118 citations

Bempedoic Acid and Cardiovascular Outcomes in Statin-Intolerant Patients

New England Journal of Medicine2023-03-04752 citations

Effect of bempedoic acid plus ezetimibe fixed-dose combination vs ezetimibe or placebo on low-density lipoprotein cholesterol in patients with type 2 diabetes and hypercholesterolemia not treated with statins.

2021-10-0413 citations

Association of Bempedoic Acid Administration With Atherogenic Lipid Levels in Phase 3 Randomized Clinical Trials of Patients With Hypercholesterolemia

JAMA Cardiology2020-07-01178 citations

Bempedoic acid plus ezetimibe fixed-dose combination in patients with hypercholesterolemia and high CVD risk treated with maximally tolerated statin therapy

European Journal of Preventive Cardiology2019-07-29342 citations