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Bedaquiline (B)

DRUG5 trials

Sponsors

University College, London, Shenzhen Third People's Hospital, Shanghai Pulmonary Hospital, Shanghai, China, Vancouver Coastal Health

Conditions

Drug-Susceptible Pulmonary TuberculosisMycobacterium Abscessus InfectionNon-Tuberculous Mycobacterial (NTM) PneumoniaPulmonary TuberculosisTuberculosis, Pulmonary

Phase 1

Bacteriophage Therapy for Mycobacterium Abscessus Pulmonary Infection
Enrolling by invitationNCT07228702
Vancouver Coastal HealthMycobacterium Abscessus Infection, Non-Tuberculous Mycobacterial (NTM) Pneumonia
Start: 2025-11-30End: 2027-10-31Target: 1Updated: 2025-11-17

Phase 2

Platform Assessing Regimens and Durations In a Global Multisite Consortium for TB
RecruitingNCT06114628
University College, LondonPulmonary Tuberculosis
Start: 2024-01-09End: 2027-08-11Target: 2500Updated: 2025-10-06
Short-Course Regimen With Bedaquiline, Moxifloxacin and Pyrazinamide for Early Bactericidal Activity in Drug-Susceptible Tuberculosis
Not yet recruitingNCT07129629
Shanghai Pulmonary Hospital, Shanghai, ChinaDrug-Susceptible Pulmonary Tuberculosis, Tuberculosis, Pulmonary
Start: 2025-08-20End: 2027-12-31Target: 45Updated: 2025-08-19

Phase 3

A PAN-USR TB Multi-Center Trial
RecruitingNCT06905522
Shenzhen Third People's HospitalPulmonary Tuberculosis
Start: 2025-06-18End: 2029-12-31Target: 610Updated: 2025-12-01
Ultra-Short Regimen for Elderly DS-TB
Not yet recruitingNCT07076225
Shenzhen Third People's HospitalPulmonary Tuberculosis
Start: 2025-07-25End: 2030-07-31Target: 300Updated: 2025-07-22