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Becotatug Vedotin (MRG003)

DRUG3 trials

Sponsors

West China Second University Hospital, Sun Yat-sen University, Fudan University

Conditions

Advanced or Metastatic Breast Cancer (BC)Advanced or Metastatic Pancreatic AdenocarcinomaBecotatug VedotinGastric CancerGastroesophageal Junction (GEJ) AdenocarcinomaHead and Neck CancerLocally Advanced Head and Neck CancerNeoadjuvant Therapy

Phase 2

Becotatugvedotin Plus Pucotenlimab in EGFR-Positive Advanced Gastric/GEJ Adenocarcinoma
Not yet recruitingNCT07692334
West China Second University HospitalBecotatug Vedotin, Gastric Cancer, Gastroesophageal Junction (GEJ) Adenocarcinoma +1
Start: 2026-07-20End: 2027-12-31Target: 28Updated: 2026-07-09
Neoadjuvant Presurgical Becotatug Vedotin (MRG003) Plus Pucotenlimab (HX008) in Oral Cavity Squamous Cell Carcinoma
Not yet recruitingNCT07766889
Sun Yat-sen UniversityHead and Neck Cancer, Locally Advanced Head and Neck Cancer, Neoadjuvant Therapy +1
Start: 2026-09-01End: 2028-12-31Target: 32Updated: 2026-08-17
Protein-Matched ADC or PDC Umbrella Trial in Advanced Pancreatic and Breast Cancer
Not yet recruitingNCT07825753
Fudan UniversityAdvanced or Metastatic Breast Cancer (BC), Advanced or Metastatic Pancreatic Adenocarcinoma
Start: 2026-09-10End: 2030-02-01Target: 225Updated: 2026-09-17