BAY 2433334
Sponsors
Bayer AG
Conditions
Prevention of ischemic stroke in patients post acute non-cardioembolic ischemic stroke or high-risk transient ischemic attackPrevention of stroke or systemic embolism in atrial fibrillationPrevention of thromboembolic events
Phase 1
Phase 3
(19767 OCEANIC-AF) A multicenter, international, randomized, active comparator-controlled, double-blind, double-dummy, parallel-group, 2-arm, Phase 3 study to compare the efficacy and safety of the oral FXIa inhibitor asundexian (BAY 2433334) with apixaban for the prevention of stroke or systemic embolism in male and female participants aged 18 years and older with atrial fibrillation at risk for stroke
CompletedCTIS2023-503794-38-00
Start: 2022-11-24End: 2024-01-23Target: 9578Updated: 2023-10-26
(20604 OCEANIC STROKE) A multicenter, randomized, placebo controlled, double-blind, parallel group and event driven Phase 3 study of the oral FXIa inhibitor asundexian (BAY 2433334) for the prevention of ischemic stroke in male and female participants aged 18 years and older after an acute non-cardioembolic ischemic stroke or high-risk TIA
CompletedCTIS2023-503793-20-00
Start: 2023-01-18End: 2025-10-23Target: 5223Updated: 2025-10-29