Azvudine

DRUG12 trials

Conditions

AzvudineCOVID-19COVID-19 Respiratory InfectionChronic Hepatitis BSARS-CoV-2 Infection

Phase 2

Evaluate the Efficacy and Safety of Azvudine in Preventing SARS-Cov-2 Infection in Household Contacts of Covid-19

NCT05633433

Shanghai Henlius BiotechSARS-CoV-2 Infection

Start: 2022-12-29End: 2024-07-15Target: 1550Updated: 2023-01-09

Evaluate Azvudine in Preventing SARS-Cov-2 Infection in Household Contacts of Covid-19 in China

NCT05682599

Shanghai Henlius BiotechCOVID-19

Start: 2023-01-06End: 2023-05-15Target: 300Updated: 2023-01-31

Multicenter Randomized Double-blind Placebo-controlled Study to Investigate Azvudine in Symptomatic Adults With COVID-19 at Increased Risk of Progressing to Severe Illness

RecruitingNCT05689034

Peking Union Medical College HospitalCOVID-19 Respiratory Infection

Start: 2023-04-19End: 2025-12-31Target: 1096Updated: 2024-11-25

Phase 3

Study on Safety and Clinical Efficacy of AZVUDINE in COVID-19 Patients (SARS-CoV-2 Infected)

CompletedNCT04668235

HRH Pharmaceuticals LimitedCOVID-19

Start: 2021-04-23End: 2022-08-10Updated: 2022-08-12

Study on Safety and Clinical Efficacy of AZVUDINE in Initial Stage COVID-19 Patients (SARS-CoV-2 Infected)

CompletedNCT05033145

HRH Pharmaceuticals LimitedCOVID-19

Start: 2022-01-15End: 2022-07-27Updated: 2022-08-12

A Small Sample Prospective Clinical Study of Azvudine Tablets to Promote Clinical Cure in Patients With Chronic Hepatitis B

RecruitingNCT07307586

Zhigang RenAzvudine, Chronic Hepatitis B

Start: 2025-09-01End: 2027-12-31Target: 120Updated: 2025-12-29

Phase 4

A Study of Efficacy and Safety of Azvudine vs. Nirmatrelvir-Ritonavir in the Treatment of COVID-19 Infection

NCT05697055

Shandong Provincial HospitalCOVID-19

Start: 2023-01-21End: 2023-07-21Target: 410Updated: 2023-02-27

Unknown Phase

An Observational, Ambispective Cohort Study of Azvudine in the Treatment of Patients With COVID-19 Pneumonia

NCT05621993

Qianfoshan HospitalCOVID-19 Respiratory Infection

Start: 2022-11-22End: 2023-12-31Target: 500Updated: 2023-10-03

The Efficacy of Azvudine and Paxlovid in High-risk Patients With COVID-19: A Prospective Randomized Controlled Trial

NCT05642910

Southeast University, ChinaSARS-CoV-2 Infection

Start: 2022-10-18End: 2023-04-30Target: 540Updated: 2022-12-08

Real-world Study Evaluating the Efficacy and Safety of Azvudine in Nursing Home Patients

NCT05675748

Shanghai Henlius BiotechCOVID-19

Start: 2023-01-15End: 2023-04-15Target: 400Updated: 2023-01-13

Risk Factors for Severe Disease in Hospitalized Patients With COVID-19 and the Effect of Azvudine Treatment: a Retrospective Cohort Study

NCT06006611

Fifth Affiliated Hospital, Sun Yat-Sen UniversityCOVID-19

Start: 2023-08-05End: 2023-10-30Target: 4201Updated: 2023-09-21

The Real-world Clinical Study of Azvudine Tablets in the Treatment of COVID-19

CompletedNCT06349655

The First Affiliated Hospital of Zhengzhou UniversityAzvudine, COVID-19

Start: 2023-12-05End: 2024-03-10Updated: 2024-04-05

BMJ Open2025-06-01

Effectiveness of azvudine versus nirmatrelvir/ritonavir for hospitalized patients with SARS-CoV-2 infection and pre-existing liver diseases.

2025-05-19

The effectiveness and safety of azvudine treatment in COVID‐19 patients with kidney disease based on a multicenter retrospective cohort study

View2025-04-09

The Antiviral Efficacy and Safety of Azvudine in Hospitalized SARS‐CoV‐2 Infected Patients with Liver Diseases Based on a Multicenter, Retrospective Cohort Study

Advanced Science2025-02-22

Antiviral effectiveness and safety of azvudine in hospitalized SARS‐CoV‐2 patients with pre‐existing chronic respiratory diseases: A multicenter, retrospective cohort study

View2025-02-05

Real-world effectiveness and safety of azvudine in hospitalized patients with SARS-CoV-2 infection: A multicenter, retrospective cohort study.

2024-11-172 citations

Efficacy and safety of azvudine in symptomatic adult COVID-19 participants who are at increased risk of progressing to critical illness: a study protocol for a multicentre randomized double-blind placebo-controlled phase III trial

Trials2024-01-221 citations

Phase III, randomized, double-blind, placebo-controlled clinical study: a study on the safety and clinical efficacy of AZVUDINE in moderate COVID-19 patients

Frontiers in Medicine2023-10-1927 citations

Serial viral load analysis by DDPCR to evaluate FNC efficacy and safety in the treatment of mild cases of COVID-19

Frontiers in Medicine2023-03-1441 citations

4′-Modified Nucleosides for Antiviral Drug Discovery: Achievements and Perspectives

Accounts of Chemical Research2022-01-2568 citations