AZD6621
Sponsors
AstraZeneca AB, Hibi Kazushige, AstraZeneca
Conditions
Metastatic Prostate CancerProstate Cancer
Phase 1
A Study to Learn How Safe AZD6621 is, How Well it Works, and How it Moves Throughout the Body Over Time, in Adult Male Participants With Metastatic Prostate Cancer
RecruitingNCT07192614
Start: 2025-09-30End: 2029-03-29Target: 52Updated: 2026-09-02
A Phase I/II Open-label, Dose Escalation and Dose Expansion Study to Evaluate the Safety, Pharmacokinetics, Pharmacodynamics, and Efficacy of AZD6621, a T Cell-engaging Antibody That Targets STEAP2, CD3, and CD8 in Adult Participants With Metastatic Prostate Cancer (ACTIVATED-4-PC)
Not yet recruitingCTIS2025-520626-37-00
Target: 45Updated: 2026-06-17