AZD5672

DRUG8 trials

Sponsors

AstraZeneca

Conditions

Healthy VolunteersPharmacokineticsRenal ImpairmentRheumatoid Arthritis

Phase 1

Mass Balance and Metabolic Profiling of [14C]AZD5672 in Healthy Male Volunteers

CompletedNCT00711074

AstraZenecaRheumatoid Arthritis

Start: 2008-06-30End: 2008-07-31Target: 4Updated: 2009-04-09

Safety Study of AZD5672 in Renally Impaired Subjects

CompletedNCT00715702

AstraZenecaRenal Impairment

Start: 2008-07-31End: 2009-02-28Target: 40Updated: 2009-04-29

Drug Interaction Study - Assess Pharmacokinetics of Both AZD5672 and Atorvastatin

CompletedNCT00722956

AstraZenecaHealthy Volunteers, Pharmacokinetics

Start: 2008-07-31End: 2008-08-31Target: 12Updated: 2010-12-02

Drug Interaction Study - Effect of AZD5672 on the Pharmacokinetics of Digoxin

CompletedNCT00723424

AstraZenecaHealthy Volunteers, Pharmacokinetics

Start: 2008-07-31End: 2008-12-31Target: 24Updated: 2010-12-02

AZD5672 Absolute Bioavailability Study

CompletedNCT00746837

AstraZenecaHealthy Volunteers

Start: 2008-08-31End: 2009-01-31Target: 26Updated: 2010-12-02

AZD5672 Bioavailability Study in Healthy Male and Female Subjects

CompletedNCT00871767

AstraZenecaRheumatoid Arthritis

Start: 2009-03-31End: 2009-05-31Target: 24Updated: 2009-06-30

A Study to Investigate the Potential for AZD5672 to Affect the Electrical Conduction Pathways in the Heart

CompletedNCT00887770

AstraZenecaRheumatoid Arthritis

Start: 2009-04-30End: 2009-07-31Target: 64Updated: 2009-07-16

Phase 2

A Proof of Concept and Dose Ranging Study in Patients With Rheumatoid Arthritis

CompletedNCT00713544

AstraZenecaRheumatoid Arthritis

Start: 2008-07-31End: 2009-04-30Updated: 2011-10-03