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AZD5004

DRUG13 trials

Sponsors

AstraZeneca AB, AstraZeneca, Eccogene

Conditions

Diabetes Mellitus, Type 2Healthy ParticipantsHepatic ImpairmentObesity or OverweightParticipants living with Obesity or Overweight with at least 1 comorbidityRenal ImpairmentType 2 DiabetesType 2 Diabetes Mellitus

Phase 1

A Study to Investigate Multiple Ascending Doses and Relative Bioavailability of AZD5004 in Healthy Participants
CompletedNCT06555822
AstraZenecaHealthy Participants
Start: 2024-08-15End: 2025-03-06Updated: 2025-03-17
A Phase I Study to Investigate the Effect of Renal Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD5004
CompletedNCT06742762
AstraZenecaRenal Impairment
Start: 2024-12-17End: 2025-04-20Updated: 2025-06-08
Study to Investigate the Effect of Hepatic Impairment on the Pharmacokinetics, Safety, and Tolerability of AZD5004
CompletedNCT06813781
AstraZenecaHepatic Impairment
Start: 2024-12-19End: 2025-10-02Updated: 2025-10-15
A Study to Investigate the Impact of Multiple Doses of Itraconazole on AZD5004 in Healthy Participants and Multiple Doses of AZD5004 on Combined Oral Ethinyl Oestradiol and Levonorgestrel in Healthy Female Participants
CompletedNCT06942936
AstraZenecaHealthy Participants
Start: 2025-05-28End: 2026-01-28Updated: 2026-02-03
A Study to Investigate the Effect of AZD5004 on Rosuvastatin, Atorvastatin, Simvastatin, Repaglinide and the Effect of Erythromycin on AZD5004 in Healthy Participants
CompletedNCT06948747
AstraZenecaHealthy Participants
Start: 2025-05-06End: 2025-10-03Updated: 2025-10-10
A Phase Ib Study of AZD5004 in Chinese Participants With Overweight/Obesity With or Without Type 2 Diabetes Mellitus
CompletedNCT06988553
EccogeneObesity or Overweight, Type 2 Diabetes
Start: 2025-06-17End: 2025-11-28Updated: 2025-12-23
A Study in Healthy Participants to Investigate Relative Bioavailability of AZD5004 in Three Solid Oral Formulations
CompletedNCT06996886
AstraZenecaHealthy Participants
Start: 2025-05-22End: 2025-07-25Updated: 2025-07-31
A Study to Investigate the Effect of AZD5004 on Mitiglinide and Pioglitazone in Healthy Participants
RecruitingNCT07444424
AstraZenecaHealthy Participants
Start: 2026-03-13End: 2026-07-02Target: 32Updated: 2026-03-30
A Study to Investigate the Pharmacokinetics of Different Formulations and Safety of AZD5004 in Healthy Participants Aged 18 to 55 Years
RecruitingNCT07455825
AstraZenecaHealthy Participants
Start: 2026-03-05End: 2026-06-01Target: 64Updated: 2026-03-12

Phase 2

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